Carbazole

Carbazole

SCHEMBL5795709

c1ccc(-c2ccccc2-c2ccccc2)cc1.c1ccc2c(c1)[nH]c1ccccc12.c1ccc2c(c1)[nH]c1ccccc12

nearest known ligand 0.67

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 0.67
HSD17B10 Q99714 4/20 0.67
GPR3 P46089 2/20 0.67
HPGD P15428 6/20 0.59
SMN1; SMN2 Q16637 3/20 0.59
HTT P42858 2/20 0.59
MAPK1 P28482 1/20 0.59
AHR P35869 1/20 0.56
ESR1 P03372 1/20 0.54
ESR2 Q92731 1/20 0.54
KDM4E B2RXH2 6/20 0.50
LMNA P02545 3/20 0.50
GAA P10253 2/20 0.50
GLA P06280 1/20 0.50
ATM Q13315 1/20 0.50
EGFR P00533 1/20 0.48
TDO2 P48775 2/20 0.47
HTR2B P41595 1/20 0.47
HTR5A P47898 1/20 0.47
CYP19A1 P11511 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Carbazole SCHEMBL27734322 1.00 ALDH1A1 (0.67) ALDH1A1HSD17B10GPR3HPGDSMN1; SMN2
Carbazole SCHEMBL29177992 0.90 ALDH1A1 (0.54) ALDH1A1HSD17B10GPR3HPGDSMN1; SMN2
SCHEMBL5488320 0.88 AHR (0.55) ALDH1A1HSD17B10GPR3HPGDSMN1; SMN2
SCHEMBL3417429 0.88 AHR (0.55) ALDH1A1HSD17B10GPR3HPGDSMN1; SMN2
Carbazole SCHEMBL433857 0.87 ALDH1A1 (0.78) ALDH1A1HSD17B10GPR3HPGDSMN1; SMN2
Carbazole SCHEMBL29177816 0.87 ALDH1A1 (0.78) ALDH1A1HSD17B10GPR3HPGDSMN1; SMN2
Carbazole SCHEMBL51051 0.87 ALDH1A1 (0.78) ALDH1A1HSD17B10GPR3HPGDSMN1; SMN2
Carbazole SCHEMBL29177761 0.87 ALDH1A1 (0.78) ALDH1A1HSD17B10GPR3HPGDSMN1; SMN2
Carbazole SCHEMBL28477873 0.87 ESR1 (0.57) ALDH1A1HSD17B10GPR3HPGDSMN1; SMN2
Carbazole SCHEMBL29177682 0.87 ALDH1A1 (0.50) ALDH1A1HSD17B10GPR3HPGDSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2006047119-A1 ARYLCARBAZ AS HOSTS IN PHOSPHORESCENT ORGANIC LIGHT EMITTING DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2006-05-04 WO disclosed