Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | TSHR | P16473 | 3/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | ACHE | P22303 | 1/20 | 0.43 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | AOX1 | Q06278 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24984756 | 0.85 | MAPT (0.41) | PTPN1ALDH1A1TSHRNPSR1KCNH2 | |
| SCHEMBL7161220 | 0.84 | PGK1 (0.38) | PTPN1ALDH1A1TSHRNPSR1KCNH2 | |
| SCHEMBL2036856 | 0.84 | PGK1 (0.38) | PTPN1ALDH1A1TSHRNPSR1KCNH2 | |
| SCHEMBL8419113 | 0.83 | SRD5A2 (0.45) | PTPN1ALDH1A1TSHRMEN1KMT2A | |
| SCHEMBL14303549 | 0.83 | PTPN5 (0.50) | ALDH1A1TSHRNPSR1KCNH2ACHE | |
| SCHEMBL13337650 | 0.82 | NPSR1 (0.48) | ALDH1A1TSHRNPSR1KCNH2POLB | |
| Hydrochloric Acid SCHEMBL5215511 | 0.82 | MAOB (0.37) | ALDH1A1TSHRNPSR1KCNH2LMNA | |
| SCHEMBL642867 | 0.82 | TSHR (0.47) | PTPN1ALDH1A1TSHRNPSR1LMNA | |
| SCHEMBL7182139 | 0.81 | PTPN1 (0.39) | PTPN1ALDH1A1TSHRNPSR1KCNH2 | |
| SCHEMBL7598722 | 0.81 | PTPN1 (0.39) | PTPN1ALDH1A1TSHRNPSR1KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115776891-A | STAT degradants and uses thereof | 凯麦拉医疗公司 | 2023-03-10 | — | — | CN | disclosed |
| CN-115677831-A | Peptidomimetic STAT degradation drug, composition and application | 杭州和正医药有限公司 | 2023-02-03 | — | — | CN | disclosed |
| CN-114269763-A | Small molecule degradant for STAT3 | 美国密歇根州立大学试剂中心 | 2022-04-01 | — | — | CN | disclosed |
| CN-106471004-A | TC PTP inhibitor as the APC activator for immunotherapy | 麦吉尔大学学术发展皇家学院 | 2017-03-01 | — | — | CN | disclosed |
| WO-2006037090-A2 | DRUG-PHOSPHATE CONJUGATES AS PRODRUGS | PURDUE RESEARCH FOUNDATION (US) | 2006-04-06 | — | — | WO | disclosed |