SCHEMBL5798706

SCHEMBL5798706

NOCCCc1ccc(F)cc1

nearest known ligand 0.63

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
IDO1 P14902 4/20 0.63
AGXT P21549 2/20 0.56
TAAR1 Q96RJ0 3/20 0.52
MAOB P27338 2/20 0.45
LOXL2 Q9Y4K0 1/20 0.44
AOC3 Q16853 1/20 0.44
CYP19A1 P11511 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8973679 0.94 IDO1 (0.55) IDO1AGXTTAAR1MAOBLOXL2
SCHEMBL5795896 0.86 IDO1 (0.60) IDO1AGXTTAAR1MAOBLOXL2
SCHEMBL29076614 0.82 TAAR1 (0.50) IDO1AGXTTAAR1MAOBLOXL2
SCHEMBL15107958 0.78 IDO1 (0.63) IDO1
SCHEMBL13669594 0.78 IDO1 (0.63) IDO1TAAR1
SCHEMBL2153837 0.78 TAAR1 (0.47) IDO1AGXTTAAR1MAOBAOC3
SCHEMBL9672758 0.78 IDO1 (0.63) IDO1AGXTTAAR1MAOBAOC3
SCHEMBL2320532 0.78 TAAR1 (0.62) IDO1AGXTTAAR1MAOBLOXL2
SCHEMBL10574057 0.78 TAAR1 (0.62) IDO1AGXTTAAR1MAOBLOXL2
SCHEMBL5799131 0.78 IDO1 (0.60) IDO1AGXTTAAR1MAOB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2006037496-A1 POLYHALOGENATED PROPENE BENZOQUINONE DIOXIME DERIVATIVES AND ITS USE AS PESTICIDES BAYER CROPSCIENCE AG (DE) 2006-04-13 WO disclosed
WO-2005095330-A1 NOVEL DICHLOROPROPENE DERIVATIVES BAYER CROPSCIENCE AG (DE) 2005-10-13 WO disclosed