Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 4/20 | 0.51 |
| ▸ | MAOB | P27338 | 4/20 | 0.32 |
| ▸ | CALML3 | P27482 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.31 |
| ▸ | SDHA | P31040 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5795992 | 1.00 | MAOA (0.51) | MAOAMAOBCALML3LMNAPTGS1 | |
| SCHEMBL5795169 | 0.88 | MAOA (0.39) | MAOAMAOBCALML3LMNAPTGS1 | |
| SCHEMBL3034814 | 0.87 | MAOA (0.55) | MAOAMAOBCALML3LMNAPTGS1 | |
| SCHEMBL3034811 | 0.87 | MAOA (0.55) | MAOAMAOBCALML3LMNAPTGS1 | |
| SCHEMBL3038817 | 0.87 | MAOA (0.55) | MAOAMAOBCALML3LMNAPTGS1 | |
| SCHEMBL5795260 | 0.87 | MAOA (0.67) | MAOAMAOBCALML3LMNAPTGS1 | |
| SCHEMBL5792925 | 0.87 | MAOA (0.67) | MAOAMAOBCALML3LMNAPTGS1 | |
| SCHEMBL5792480 | 0.82 | MAOA (0.46) | MAOA | |
| SCHEMBL5792883 | 0.82 | MAOA (0.46) | MAOA | |
| SCHEMBL13515461 | 0.80 | MAOA (0.59) | MAOAMAOBCALML3LMNAPTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1478629-B1 | N-ARYL-2-OXAZOLIDINONE-5-CARBOXAMIDES AND THEIR DERIVATIVES AND THEIR USE AS ANTIBACTERIALS | PHARMACIA & UPJOHN CO LLC (US) | 2006-10-11 | — | — | EP | claimed |