Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 13/20 | 0.42 |
| ▸ | PTGS1 | P23219 | 4/20 | 0.41 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.38 |
| ▸ | CNR1 | P21554 | 1/20 | 0.37 |
| ▸ | CNR2 | P34972 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CA4 | P22748 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5559062 | 0.94 | PTGS2 (0.46) | PTGS2PTGS1HRH4HDAC3HDAC1 | |
| SCHEMBL5558905 | 0.93 | PTGS2 (0.42) | PTGS2PTGS1HRH4CNR1CNR2 | |
| SCHEMBL5554446 | 0.91 | PTGS2 (0.48) | PTGS2PTGS1CNR1CNR2KMT2A | |
| SCHEMBL6460231 | 0.89 | PTGS2 (0.37) | PTGS2PTGS1 | |
| SCHEMBL5558678 | 0.89 | PTGS2 (0.51) | PTGS2PTGS1HRH4HDAC3HDAC1 | |
| SCHEMBL5559076 | 0.87 | PTGS2 (0.51) | PTGS2PTGS1HRH4HDAC3HDAC1 | |
| SCHEMBL6424090 | 0.86 | PTGS2 (0.44) | PTGS2PTGS1HRH4HDAC3HDAC1 | |
| SCHEMBL5558923 | 0.86 | AKR1C3 (0.41) | PTGS2PTGS1MEN1KMT2A | |
| SCHEMBL5558847 | 0.85 | AKR1C3 (0.42) | PTGS2PTGS1HRH4MEN1KMT2A | |
| SCHEMBL5558568 | 0.85 | PTGS2 (0.45) | PTGS2PTGS1HRH4HDAC3HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006050120-A2 | SYNTHESIS OF COX-2 AND FAAH INHIBITORS | MICROBIA, INC. (US) | 2006-05-11 | — | — | WO | disclosed |