Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 18/20 | 0.55 |
| ▸ | PTGS1 | P23219 | 4/20 | 0.51 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.49 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.46 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5554756 | 0.93 | PTGS2 (0.58) | PTGS2PTGS1HRH4HDAC3HDAC1 | |
| SCHEMBL5561002 | 0.93 | PTGS2 (0.63) | PTGS2 | |
| SCHEMBL5561007 | 0.93 | PTGS2 (0.63) | PTGS2 | |
| SCHEMBL5560391 | 0.87 | PTGS2 (0.55) | PTGS2PTGS1HRH4HDAC3HDAC1 | |
| SCHEMBL5811926 | 0.85 | PTGS2 (0.56) | PTGS2PTGS1HRH4HDAC3HDAC1 | |
| SCHEMBL5560380 | 0.84 | PTGS2 (0.52) | PTGS2PTGS1 | |
| SCHEMBL6423094 | 0.84 | PTGS2 (0.52) | PTGS2PTGS1 | |
| SCHEMBL5798070 | 0.84 | PTGS2 (0.47) | PTGS2PTGS1HRH4HDAC3HDAC1 | |
| SCHEMBL5558622 | 0.84 | PTGS2 (0.65) | PTGS2 | |
| SCHEMBL5555386 | 0.84 | PTGS2 (0.60) | PTGS2PTGS1HRH4HDAC3HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006050120-A2 | SYNTHESIS OF COX-2 AND FAAH INHIBITORS | MICROBIA, INC. (US) | 2006-05-11 | — | — | WO | disclosed |