Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 10/20 | 0.37 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | CXCL8 | P10145 | 1/20 | 0.34 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.33 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.32 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.32 |
| ▸ | ESRRG | P62508 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5812734 | 0.94 | HPGD (0.41) | PTGS2PTGS1POLBHPGDHTT | |
| SCHEMBL5562449 | 0.93 | PTGS2 (0.33) | PTGS2PTGS1AKR1C3AKR1C2 | |
| SCHEMBL5562450 | 0.93 | PTGS2 (0.33) | PTGS2PTGS1AKR1C3AKR1C2 | |
| SCHEMBL5800851 | 0.92 | PTGS2 (0.37) | PTGS2PTGS1HRH4AKR1C3AKR1C2 | |
| SCHEMBL5555232 | 0.91 | AKR1C3 (0.38) | PTGS2PTGS1AKR1C3AKR1C2 | |
| SCHEMBL5555246 | 0.91 | AKR1C3 (0.38) | PTGS2PTGS1AKR1C3AKR1C2 | |
| SCHEMBL5808507 | 0.91 | PTGS2 (0.46) | PTGS2PTGS1HRH4AKR1C3AKR1C2 | |
| SCHEMBL5560275 | 0.89 | HIF1A (0.37) | PTGS2PTGS1AKR1C3AKR1C2 | |
| SCHEMBL5801605 | 0.89 | PTGS2 (0.47) | PTGS2PTGS1CXCL8HRH4AKR1C3 | |
| SCHEMBL5813354 | 0.89 | PTGS2 (0.37) | PTGS2PTGS1HRH4AKR1C3AKR1C2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006050120-A2 | SYNTHESIS OF COX-2 AND FAAH INHIBITORS | MICROBIA, INC. (US) | 2006-05-11 | — | — | WO | disclosed |