SCHEMBL5796838

SCHEMBL5796838

CC(C)(C)c1ccc(N2c3ccc(N4c5ccccc5Sc5ccccc54)cc3Sc3cc(N4c5ccccc5Sc5ccccc54)ccc32)cc1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HDAC6 Q9UBN7 2/20 0.48
NOX1 Q9Y5S8 4/20 0.42
ADRA2A P08913 2/20 0.42
SLC6A2 P23975 2/20 0.42
SLC6A4 P31645 2/20 0.42
DRD3 P35462 2/20 0.42
MEN1 O00255 2/20 0.42
KMT2A Q03164 2/20 0.42
ADRA2B P18089 1/20 0.42
ADRA2C P18825 1/20 0.42
CHRM3 P20309 1/20 0.42
HTR2C P28335 1/20 0.42
HTR2B P41595 1/20 0.42
L3MBTL1 Q9Y468 1/20 0.42
MAOA P21397 1/20 0.41
BCHE P06276 5/20 0.37
CYP2D6 P10635 2/20 0.36
CYP3A4 P08684 1/20 0.36
CYP2C19 P33261 1/20 0.36
PMM2 O15305 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5795307 0.92 HDAC6 (0.54) HDAC6NOX1ADRA2ASLC6A2SLC6A4
SCHEMBL5798501 0.91 HDAC6 (0.46) HDAC6NOX1ADRA2ASLC6A2SLC6A4
SCHEMBL13889525 0.90 HDAC6 (0.45) HDAC6NOX1ADRA2ASLC6A2SLC6A4
SCHEMBL5795297 0.89 HDAC6 (0.47) HDAC6NOX1ADRA2ASLC6A2SLC6A4
SCHEMBL19862774 0.88 HDAC6 (0.44) HDAC6NOX1ADRA2ASLC6A2SLC6A4
SCHEMBL29313221 0.81 HDAC6 (0.38) HDAC6NOX1ADRA2ASLC6A2SLC6A4
SCHEMBL13125121 0.81 HDAC6 (0.38) HDAC6NOX1ADRA2ASLC6A2SLC6A4
SCHEMBL16940906 0.81 MAOA (0.43) HDAC6NOX1ADRA2ASLC6A2SLC6A4
SCHEMBL17278630 0.81 HDAC6 (0.48) HDAC6MEN1KMT2AL3MBTL1MAOA
SCHEMBL13008629 0.81 HDAC6 (0.39) HDAC6NOX1ADRA2ASLC6A2SLC6A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2006041263-A1 CHROMOPHORE COMPOUNDS AND ORGANIC ELECTROLUMINESCENC DISPLAY DEVICE COMPRISING THE SAME DOOSAN CORPORATION (KR) 2006-04-20 WO disclosed