Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 3/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.51 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | CACNA1B | Q00975 | 3/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.46 |
| ▸ | TRPV6 | Q9H1D0 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5796879 | 1.00 | FAAH (0.52) | FAAHKDM4EHRH3ALDH1A1TDP1 | |
| SCHEMBL5796881 | 1.00 | FAAH (0.52) | FAAHKDM4EHRH3ALDH1A1TDP1 | |
| SCHEMBL5792971 | 0.91 | HRH3 (0.57) | HRH3CACNA1BSLC2A1 | |
| SCHEMBL5792965 | 0.91 | HRH3 (0.57) | HRH3CACNA1BSLC2A1 | |
| SCHEMBL5792968 | 0.91 | HRH3 (0.57) | HRH3CACNA1BSLC2A1 | |
| SCHEMBL5796712 | 0.90 | FAAH (0.55) | FAAHKDM4EHRH3ALDH1A1HPGD | |
| SCHEMBL5796707 | 0.90 | FAAH (0.55) | FAAHKDM4EHRH3ALDH1A1HPGD | |
| SCHEMBL5796709 | 0.90 | FAAH (0.55) | FAAHKDM4EHRH3ALDH1A1HPGD | |
| SCHEMBL5793644 | 0.89 | HRH3 (0.56) | FAAHKDM4EHRH3ALDH1A1CYP2D6 | |
| SCHEMBL5793639 | 0.89 | HRH3 (0.56) | FAAHKDM4EHRH3ALDH1A1CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006024955-A1 | AZABICYCLIC AMINE HISTAMINE-3 RECEPTOR ANTAGONISTS | PFIZER PRODUCTS INC. (US) | 2006-03-09 | — | — | WO | claimed |
| US-20060047114-A1 | Azabicyclic amine histamine-3 receptor antagonists | PFIZER INC | 2006-03-02 | — | — | US | claimed |
| US-20060047114-A1 | Azabicyclic amine histamine-3 receptor antagonists | PFIZER INC | 2006-03-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060047114-A1 | Azabicyclic amine histamine-3 receptor antagonists | HRH3, HRH4, HRH2 | FAAH 151/4885KDM4E 2069/4885HRH3 1/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.