Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 5/20 | 0.65 |
| ▸ | RAB9A | P51151 | 5/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.52 |
| ▸ | MEN1 | O00255 | 4/20 | 0.52 |
| ▸ | ATM | Q13315 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 5/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.45 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.45 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.44 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.44 |
| ▸ | GFER | P55789 | 1/20 | 0.43 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5797991 | 0.85 | NPC1 (0.59) | NPC1RAB9AKMT2AMEN1ATM | |
| SCHEMBL5797579 | 0.84 | KMT2A (0.55) | NPC1RAB9AKMT2AMEN1ATM | |
| SCHEMBL5794374 | 0.82 | NPC1 (0.58) | NPC1RAB9AKMT2AMEN1ATM | |
| SCHEMBL5794603 | 0.82 | MEN1 (0.52) | NPC1RAB9AKMT2AMEN1ATM | |
| SCHEMBL3870499 | 0.80 | MEN1 (0.75) | NPC1RAB9AKMT2AMEN1ATM | |
| SCHEMBL3591205 | 0.80 | NPC1 (0.59) | NPC1RAB9AKMT2AMEN1ATM | |
| SCHEMBL5797569 | 0.80 | KMT2A (0.59) | NPC1RAB9AKMT2AMEN1ATM | |
| SCHEMBL5797568 | 0.80 | ALDH1A1 (0.52) | NPC1RAB9AKMT2AMEN1ATM | |
| SCHEMBL7530863 | 0.80 | NPC1 (0.66) | NPC1RAB9AKMT2AMEN1MAPT | |
| SCHEMBL7626845 | 0.80 | ALDH1A1 (0.52) | NPC1RAB9AKMT2AMEN1ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006025717-A1 | PYRROLO[2,3-c]PYRIDINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | YUHAN CORPORATION (KR) | 2006-03-09 | — | — | WO | disclosed |