Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.56 |
| ▸ | NPC1 | O15118 | 5/20 | 0.47 |
| ▸ | RAB9A | P51151 | 4/20 | 0.47 |
| ▸ | MEN1 | O00255 | 4/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | LTA4H | P09960 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 5/20 | 0.43 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.42 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 4/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | GFER | P55789 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27924590 | 0.93 | ALDH1A1 (0.55) | ALDH1A1NPC1RAB9AMEN1KMT2A | |
| SCHEMBL5797530 | 0.85 | ALDH1A1 (0.59) | ALDH1A1NPC1RAB9AMEN1KMT2A | |
| SCHEMBL31701918 | 0.83 | ALDH1A1 (0.60) | ALDH1A1NPC1RAB9AMEN1KMT2A | |
| SCHEMBL23343548 | 0.82 | ALDH1A1 (0.59) | ALDH1A1NPC1RAB9AMEN1KMT2A | |
| SCHEMBL8564326 | 0.82 | ALDH1A1 (0.59) | ALDH1A1NPC1RAB9AMEN1KMT2A | |
| SCHEMBL27829038 | 0.81 | ALDH1A1 (0.57) | ALDH1A1NPC1RAB9AMEN1KMT2A | |
| SCHEMBL1345767 | 0.81 | ALDH1A1 (0.57) | ALDH1A1NPC1RAB9AMEN1KMT2A | |
| SCHEMBL2368431 | 0.80 | ALDH1A1 (0.56) | ALDH1A1NPC1RAB9AMEN1KMT2A | |
| SCHEMBL19172851 | 0.80 | ALDH1A1 (0.56) | ALDH1A1NPC1RAB9AMEN1KMT2A | |
| SCHEMBL6376744 | 0.80 | ALDH1A1 (0.64) | ALDH1A1NPC1RAB9AMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006025717-A1 | PYRROLO[2,3-c]PYRIDINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | YUHAN CORPORATION (KR) | 2006-03-09 | — | — | WO | disclosed |