Ethylene Glycol

Ethylene Glycol

SCHEMBL5797276

C=CC(=O)OC(=O)CC(C)=O.OCCO

nearest known ligand 0.43

Full drug profile on Sugi Atlas →

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
MGAM O43451 1/20 0.43
GAA P10253 1/20 0.43
SI P14410 1/20 0.43
MGAM2 Q2M2H8 1/20 0.43
TSHR P16473 7/20 0.42
ALDH1A1 P00352 6/20 0.34
TP53 P04637 3/20 0.34
HIF1A Q16665 3/20 0.34
CYP3A4 P08684 2/20 0.34
MAPK1 P28482 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.34
HPGD P15428 1/20 0.34
HSD17B10 Q99714 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL867454 0.94 MGAM (0.48) MGAMGAASIMGAM2TSHR
1,4-Butanediol SCHEMBL5799331 0.92 MGAM (0.40) MGAMGAASIMGAM2TSHR
Propylene Glycol SCHEMBL5799048 0.85 TSHR (0.39) MGAMGAASIMGAM2TSHR
SCHEMBL8009053 0.80 TSHR (0.42) MGAMGAASIMGAM2TSHR
Ethylene Glycol SCHEMBL28296153 0.79 TSHR (0.48) TSHRALDH1A1TP53HIF1ACYP3A4
Ethylene Glycol SCHEMBL27849780 0.78 TSHR (0.56) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL5138142 0.77 MGAM (0.48) MGAMGAASIMGAM2TSHR
SCHEMBL29088972 0.76 MGAM (0.52) MGAMGAASIMGAM2TSHR
SCHEMBL4320615 0.76 MGAM (0.52) MGAMGAASIMGAM2TSHR
Ethylene Glycol SCHEMBL28791231 0.76 MGAM (0.52) MGAMGAASIMGAM2TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2006024885-A1 PROCESS FOR THE PREPARATION OF POLYISOCYANATE/POLYSILICIC ACID BASED POLYADDITION AND HYBRID RESINS USING BLOCKED POLYISO-CYANATES AND BLOCKED POLYISOCYANATES USABLE IN THE PROCESS POLINVENT FEJLESZTO, KIVITELEZO ÉS ÉRTÉKESÍTO KFT (HU) 2006-03-09 WO claimed
WO-2006024885-A1 PROCESS FOR THE PREPARATION OF POLYISOCYANATE/POLYSILICIC ACID BASED POLYADDITION AND HYBRID RESINS USING BLOCKED POLYISO-CYANATES AND BLOCKED POLYISOCYANATES USABLE IN THE PROCESS POLINVENT FEJLESZTO, KIVITELEZO ÉS ÉRTÉKESÍTO KFT (HU) 2006-03-09 WO disclosed