Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 6/20 | 0.69 |
| ▸ | PTGS2 | P35354 | 6/20 | 0.69 |
| ▸ | AKR1C3 | P42330 | 8/20 | 0.55 |
| ▸ | AKR1C2 | P52895 | 8/20 | 0.55 |
| ▸ | ABCB1 | P08183 | 4/20 | 0.51 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.51 |
| ▸ | AKR1C4 | P17516 | 2/20 | 0.51 |
| ▸ | AKR1C1 | Q04828 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.51 |
| ▸ | GLO1 | Q04760 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | PTGES | O14684 | 1/20 | 0.51 |
| ▸ | ABCC3 | O15438 | 1/20 | 0.51 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.51 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6425519 | 0.92 | PTGS2 (0.55) | PTGS1PTGS2AKR1C3AKR1C2ABCB1 | |
| SCHEMBL5558543 | 0.89 | PTGS2 (0.70) | PTGS1PTGS2AKR1C3AKR1C2ABCB1 | |
| SCHEMBL5435359 | 0.88 | PTGS1 (0.88) | PTGS1PTGS2AKR1C3AKR1C2ABCB1 | |
| SCHEMBL5561152 | 0.86 | PTGS2 (0.63) | PTGS1PTGS2AKR1C3AKR1C2ABCB1 | |
| SCHEMBL5800524 | 0.86 | AKR1C3 (0.50) | PTGS1PTGS2AKR1C3AKR1C2ABCB1 | |
| SCHEMBL6425491 | 0.86 | PTGS2 (0.53) | PTGS1PTGS2ABCB1HIF1ALMNA | |
| SCHEMBL5800060 | 0.85 | PTGS1 (0.56) | PTGS1PTGS2AKR1C3AKR1C2ABCB1 | |
| SCHEMBL6423239 | 0.85 | PTGS2 (0.53) | PTGS1PTGS2AKR1C3AKR1C2ABCB1 | |
| SCHEMBL6428344 | 0.85 | PTGS2 (0.53) | PTGS1PTGS2AKR1C3AKR1C2ABCB1 | |
| SCHEMBL6426904 | 0.83 | PTGS1 (0.52) | PTGS1PTGS2AKR1C3AKR1C2ABCB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006050120-A2 | SYNTHESIS OF COX-2 AND FAAH INHIBITORS | MICROBIA, INC. (US) | 2006-05-11 | — | — | WO | disclosed |