Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.48 |
| ▸ | RAB9A | P51151 | 6/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.47 |
| ▸ | NPC1 | O15118 | 5/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | BLM | P54132 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.45 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.45 |
| ▸ | RELA | Q04206 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | VNN1 | O95497 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.42 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5798849 | 0.86 | MAPT (0.50) | MAPTRAB9ASMN1; SMN2NPC1ALDH1A1 | |
| SCHEMBL5797705 | 0.84 | MAPT (0.49) | MAPTRAB9ASMN1; SMN2NPC1ALDH1A1 | |
| SCHEMBL6568159 | 0.77 | PTPN1 (0.58) | MAPTRAB9ASMN1; SMN2NPC1ALDH1A1 | |
| SCHEMBL7393 | 0.77 | CA1 (0.57) | MAPTALDH1A1POLB | |
| SCHEMBL8229744 | 0.75 | PARP15 (0.65) | MAPTRAB9ASMN1; SMN2NPC1ALDH1A1 | |
| SCHEMBL19962767 | 0.75 | RAB9A (0.70) | MAPTRAB9ASMN1; SMN2NPC1ALDH1A1 | |
| Charcoal, Activated SCHEMBL31430427 | 0.75 | CA1 (0.55) | MAPTALDH1A1POLB | |
| SCHEMBL14967039 | 0.73 | MAPT (0.62) | MAPTRAB9ASMN1; SMN2NPC1ALDH1A1 | |
| SCHEMBL7401479 | 0.72 | CA1 (0.53) | MAPTPOLB | |
| SCHEMBL20764570 | 0.72 | PTPN11 (0.59) | MAPTALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006025683-A1 | ARYLAMINOMETHYL PROPENYL BENZHYDROXYAMID DERIVATIVES WITH INHIBITORY ACTIVITY AGAINST HISTONE DEACETYLASE AND METHOD FOR THE PREPARATION THEREOF | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2006-03-09 | — | — | WO | disclosed |