Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR1 | P30556 | 2/20 | 0.51 |
| ▸ | AGTR2 | P50052 | 2/20 | 0.51 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.49 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.49 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.49 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5773556 | 0.96 | AGTR1 (0.55) | AGTR1AGTR2ABCC4ABCB11PDE3B | |
| SCHEMBL5774766 | 0.94 | AGTR1 (0.55) | AGTR1AGTR2ABCC4ABCB11PDE3B | |
| SCHEMBL12730668 | 0.93 | AGTR1 (0.52) | AGTR1AGTR2ABCC4ABCB11PDE3B | |
| SCHEMBL5774997 | 0.90 | AGTR1 (0.49) | AGTR1AGTR2ABCC4ABCB11PDE3B | |
| SCHEMBL3407499 | 0.90 | AGTR1 (0.61) | AGTR1AGTR2ABCC4ABCB11PDE3B | |
| SCHEMBL5808594 | 0.88 | AGTR1 (0.49) | AGTR1AGTR2ABCC4ABCB11PDE3B | |
| SCHEMBL12730813 | 0.88 | AGTR1 (0.57) | AGTR1AGTR2ABCC4ABCB11PDE3B | |
| SCHEMBL12730676 | 0.87 | AGTR1 (0.46) | AGTR1AGTR2 | |
| SCHEMBL4960875 | 0.85 | AGTR1 (0.55) | AGTR1AGTR2ABCC4ABCB11PDE3B | |
| SCHEMBL14592214 | 0.84 | AGTR1 (0.44) | AGTR1AGTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1474417-B1 | PROCESSES FOR PREPARING LOSARTAN AND LOSARTAN POTASSIUM | TEVA PHARMA (IL) | 2006-03-22 | — | — | EP | claimed |