Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AVPR1A | P37288 | 3/20 | 0.45 |
| ▸ | GLS | O94925 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.40 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5890288 | 1.00 | AVPR1A (0.45) | AVPR1AGLSALDH1A1ALDH3A1RCE1 | |
| SCHEMBL579740 | 1.00 | AVPR1A (0.45) | AVPR1AGLSALDH1A1ALDH3A1RCE1 | |
| SCHEMBL6948748 | 0.83 | GLS (0.42) | AVPR1AGLSSMN1; SMN2HDAC1 | |
| SCHEMBL8805649 | 0.83 | GLS (0.40) | AVPR1AGLSSMN1; SMN2HDAC1 | |
| SCHEMBL28626550 | 0.82 | PIK3CD (0.51) | ALDH1A1TSHR | |
| SCHEMBL28626546 | 0.82 | PIK3CD (0.51) | ALDH1A1TSHR | |
| SCHEMBL28626548 | 0.82 | PIK3CD (0.51) | ALDH1A1TSHR | |
| SCHEMBL13104615 | 0.82 | GLS (0.46) | GLSALDH1A1SMN1; SMN2HDAC1 | |
| SCHEMBL5242251 | 0.82 | GLS (0.46) | GLSALDH1A1SMN1; SMN2HDAC1 | |
| SCHEMBL2064441 | 0.82 | GLS (0.43) | GLSALDH1A1SMN1; SMN2HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1633695-B1 | SMOOTH MUSCLE SPASMOLYTIC AGENTS | BRIDGE PHARMA INC (US) | 2012-02-15 | — | — | EP | disclosed |
| US-7141696-B2 | Smooth muscle spasmolytic agents | BRIDGE PHARMA, INC. (US) | 2006-11-28 | — | — | US | disclosed |