Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDKN1A | P38936 | 1/20 | 0.72 |
| ▸ | BRAF | P15056 | 14/20 | 0.49 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.46 |
| ▸ | PIM1 | P11309 | 1/20 | 0.46 |
| ▸ | EPHA2 | P29317 | 1/20 | 0.44 |
| ▸ | GSK3A | P49840 | 1/20 | 0.44 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5813193 | 0.89 | CDKN1A (0.76) | CDKN1ABRAFMAPK13PIM1EPHA2 | |
| SCHEMBL5799706 | 0.88 | CDKN1A (0.76) | CDKN1ABRAFMAPK13PIM1EPHA2 | |
| SCHEMBL4497345 | 0.87 | CDKN1A (0.79) | CDKN1ABRAFMAPK13PIM1EPHA2 | |
| SCHEMBL5808894 | 0.87 | CDKN1A (0.79) | CDKN1ABRAFMAPK13PIM1EPHA2 | |
| SCHEMBL5946554 | 0.87 | CDKN1A (0.71) | CDKN1ABRAFMAPK13PIM1EPHA2 | |
| SCHEMBL5613426 | 0.87 | CDKN1A (0.77) | CDKN1ABRAFMAPK13PIM1EPHA2 | |
| SCHEMBL5811516 | 0.87 | CDKN1A (0.77) | CDKN1ABRAFMAPK13PIM1EPHA2 | |
| SCHEMBL6071508 | 0.86 | CDKN1A (0.72) | CDKN1ABRAFMAPK13PIM1EPHA2 | |
| SCHEMBL5800548 | 0.86 | CDKN1A (0.80) | CDKN1ABRAFMAPK13PIM1EPHA2 | |
| SCHEMBL5821478 | 0.86 | CDKN1A (0.72) | CDKN1ABRAFMAPK13PIM1EPHA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006033796-A1 | SUBSTITUTED PYRAZOLO [1,5-a] PYRIMIDINES AND PROCESS FOR MAKING SAME | WYETH (US) | 2006-03-30 | — | — | WO | disclosed |