Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGMT | P16455 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.54 |
| ▸ | NPC1 | O15118 | 5/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.51 |
| ▸ | RAB9A | P51151 | 4/20 | 0.51 |
| ▸ | MEN1 | O00255 | 3/20 | 0.51 |
| ▸ | ATM | Q13315 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | MET | P08581 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | LTA4H | P09960 | 1/20 | 0.41 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | PTGES | O14684 | 1/20 | 0.41 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.40 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5797825 | 0.89 | ALDH1A1 (0.48) | MGMTALDH1A1NPC1KMT2ARAB9A | |
| SCHEMBL5795301 | 0.83 | NPC1 (0.56) | ALDH1A1NPC1KMT2ARAB9AMEN1 | |
| SCHEMBL5797839 | 0.83 | ALDH1A1 (0.57) | ALDH1A1NPC1KMT2ARAB9AMEN1 | |
| SCHEMBL5794222 | 0.81 | CNR2 (0.54) | ALDH1A1NPC1KMT2ARAB9AMEN1 | |
| SCHEMBL3870499 | 0.80 | MEN1 (0.75) | MGMTALDH1A1NPC1KMT2ARAB9A | |
| SCHEMBL5797569 | 0.79 | KMT2A (0.59) | MGMTALDH1A1NPC1KMT2ARAB9A | |
| SCHEMBL26917145 | 0.78 | KMT2A (0.60) | MGMTALDH1A1NPC1KMT2ARAB9A | |
| SCHEMBL29857998 | 0.78 | KMT2A (0.60) | MGMTALDH1A1NPC1KMT2ARAB9A | |
| SCHEMBL31700838 | 0.77 | ALDH1A1 (0.59) | ALDH1A1NPC1KMT2ARAB9AMEN1 | |
| Formaldehyde SCHEMBL27956172 | 0.77 | MEN1 (0.71) | MGMTALDH1A1NPC1KMT2ARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006025717-A1 | PYRROLO[2,3-c]PYRIDINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | YUHAN CORPORATION (KR) | 2006-03-09 | — | — | WO | disclosed |