SCHEMBL5797601

SCHEMBL5797601

CCc1cc(Nc2nc3ncn(CCCCN4CCOCC4)c3c(=O)[nH]2)ccc1C

nearest known ligand 0.75

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5798108 0.92 SMN1; SMN2 (0.44) SMN1; SMN2
SCHEMBL6329858 0.92
SCHEMBL5777506 0.91
SCHEMBL5776052 0.86 TK1 (0.48)
SCHEMBL5775182 0.86
SCHEMBL5775946 0.86
SCHEMBL5777237 0.85
SCHEMBL5778044 0.85 TK1 (0.48)
SCHEMBL5801063 0.85
SCHEMBL5780056 0.84

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1472254-A4 PURINE AND ISOSTERIC ANTIBACTERIAL COMPOUNDS GLSYNTHESIS INC (US) 2006-02-15 EP claimed
US-6926763-B2 Purine and isosteric antibacterial compounds GLSYNTHESIS, INC. (US) 2005-08-09 US claimed
EP-1472254-A2 PURINE AND ISOSTERIC ANTIBACTERIAL COMPOUNDS Glsynthesis Inc. (US) 2004-11-03 EP claimed
US-20040014773-A1 Purine and isosteric antibacterial compounds ACURX PHARMACEUTICALS, LLC 2004-01-22 US claimed
WO-2003066586-A2 PURINE AND ISOSTERIC ANTIBACTERIAL COMPOUNDS GLSYNTHESIS INC. (US) 2003-08-14 WO claimed
US-6926763-B2 Purine and isosteric antibacterial compounds GLSYNTHESIS, INC. (US) 2005-08-09 US disclosed
US-20040014773-A1 Purine and isosteric antibacterial compounds ACURX PHARMACEUTICALS, LLC 2004-01-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040014773-A1 Purine and isosteric antibacterial compounds MTAP, AMPD3, MPG SMN1; SMN2 2801/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.