Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.77 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.77 |
| ▸ | MAPT | P10636 | 5/20 | 0.60 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.60 |
| ▸ | POLB | P06746 | 2/20 | 0.60 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.51 |
| ▸ | RAB9A | P51151 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.48 |
| ▸ | TP53 | P04637 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | KDR | P35968 | 1/20 | 0.46 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30498938 | 0.87 | MEN1 (1.00) | MEN1KMT2AMAPTMAPK1POLB | |
| SCHEMBL393514 | 0.87 | MEN1 (1.00) | MEN1KMT2AMAPTMAPK1POLB | |
| SCHEMBL5795803 | 0.83 | KMT2A (0.71) | MEN1KMT2AMAPTMAPK1POLB | |
| SCHEMBL21046089 | 0.83 | MEN1 (0.76) | MEN1KMT2AMAPTMAPK1POLB | |
| SCHEMBL18508325 | 0.78 | MEN1 (1.00) | MEN1KMT2AMAPTMAPK1POLB | |
| SCHEMBL13437361 | 0.76 | MEN1 (0.66) | MEN1KMT2AMAPTMAPK1POLB | |
| SCHEMBL21081341 | 0.75 | MEN1 (0.64) | MEN1KMT2AMAPTMAPK1POLB | |
| SCHEMBL15227162 | 0.74 | MEN1 (0.63) | MEN1KMT2AMAPTMAPK1POLB | |
| SCHEMBL795882 | 0.74 | MEN1 (0.62) | MEN1KMT2AMAPTMAPK1POLB | |
| Methane SCHEMBL3417314 | 0.74 | MAPK1 (0.58) | MEN1KMT2AMAPK1POLBL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006025717-A1 | PYRROLO[2,3-c]PYRIDINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | YUHAN CORPORATION (KR) | 2006-03-09 | — | — | WO | disclosed |