Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 2/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.38 |
| ▸ | PPARG | P37231 | 10/20 | 0.38 |
| ▸ | PPARA | Q07869 | 5/20 | 0.38 |
| ▸ | ELANE | P08246 | 1/20 | 0.35 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.35 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5797930 | 1.00 | PTGS2 (0.39) | PTGS2HRH3PPARGPPARAELANE | |
| SCHEMBL5798186 | 0.96 | PTGS2 (0.40) | PTGS2HRH3PPARGPPARA | |
| SCHEMBL5798183 | 0.96 | PTGS2 (0.40) | PTGS2HRH3PPARGPPARA | |
| SCHEMBL5814046 | 0.94 | HRH3 (0.39) | PTGS2HRH3PPARGPPARAELANE | |
| SCHEMBL5814051 | 0.94 | HRH3 (0.39) | PTGS2HRH3PPARGPPARAELANE | |
| SCHEMBL5800015 | 0.88 | PPARG (0.37) | PTGS2HRH3PPARGPPARAAKR1C3 | |
| SCHEMBL5800017 | 0.88 | PPARG (0.37) | PTGS2HRH3PPARGPPARAAKR1C3 | |
| SCHEMBL5561287 | 0.88 | PPARG (0.37) | PTGS2HRH3PPARGPPARAAKR1C3 | |
| SCHEMBL5798899 | 0.87 | PTGS2 (0.45) | PTGS2AKR1C3AKR1C2 | |
| SCHEMBL5798896 | 0.87 | PTGS2 (0.45) | PTGS2AKR1C3AKR1C2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006050120-A2 | SYNTHESIS OF COX-2 AND FAAH INHIBITORS | MICROBIA, INC. (US) | 2006-05-11 | — | — | WO | disclosed |