Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRD5A1 | P18405 | 1/20 | 0.39 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.39 |
| ▸ | PTGER1 | P34995 | 5/20 | 0.39 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.39 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.39 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.39 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.39 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.39 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | BRD4 | O60885 | 2/20 | 0.37 |
| ▸ | CFD | P00746 | 1/20 | 0.37 |
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.37 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.36 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.36 |
| ▸ | CTSV | O60911 | 1/20 | 0.36 |
| ▸ | CTSL | P07711 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5795324 | 0.89 | TP53 (0.42) | TP53L3MBTL1BRD4MAPTSMN1; SMN2 | |
| SCHEMBL5795248 | 0.88 | SRD5A1 (0.41) | SRD5A1SRD5A2PSEN1PSEN2APH1B | |
| SCHEMBL5795079 | 0.87 | TP53 (0.39) | TP53L3MBTL1BRD4TRIM24TRIM33 | |
| SCHEMBL5793855 | 0.87 | TP53 (0.39) | TP53BRD4TRIM24TRIM33ALDH1A1 | |
| SCHEMBL5794969 | 0.86 | TP53 (0.38) | TP53L3MBTL1BRD4TRIM24TRIM33 | |
| SCHEMBL5796339 | 0.85 | CTSV (0.41) | SRD5A1SRD5A2PTGER1PSEN1PSEN2 | |
| SCHEMBL1749273 | 0.82 | PTGDR2 (0.39) | SRD5A1SRD5A2PTGER1PSEN1PSEN2 | |
| SCHEMBL5796689 | 0.81 | TP53 (0.45) | TP53L3MBTL1BRD4TRIM24TRIM33 | |
| SCHEMBL5794529 | 0.81 | TP53 (0.42) | TP53L3MBTL1BRD4TRIM24TRIM33 | |
| SCHEMBL1779402 | 0.80 | IGF1R (0.44) | SRD5A1SRD5A2L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1732546-A2 | NOVEL PYRROLO (2,3-B)PYRIDINE DERIVATIVES, THE PREPARATION AND THE PHARMACEUTICAL USE THEREOF IN THE FORM OF KINASE INHIBITORS | Aventis Pharma S.A. (FR) | 2006-12-20 | — | — | EP | disclosed |
| WO-2005095399-A2 | NOVEL PYRROLO (2,3-B)PYRIDINE DERIVATIVES, THE PREPARATION AND THE PHARMACEUTICAL USE THEREOF IN THE FORM OF KINASE INHIBITORS | AVENTIS PHARMA S.A. (FR) | 2005-10-13 | — | — | WO | disclosed |