Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.60 |
| ▸ | MAPT | P10636 | 13/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.58 |
| ▸ | USP2 | O75604 | 1/20 | 0.57 |
| ▸ | HPGD | P15428 | 1/20 | 0.56 |
| ▸ | POLB | P06746 | 3/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 5/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | SCD | O00767 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | ANO1 | Q5XXA6 | 1/20 | 0.51 |
| ▸ | ANO2 | Q9NQ90 | 1/20 | 0.51 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17383127 | 0.75 | MAPT (0.66) | TDP1MAPTKMT2AALDH1A1HPGD | |
| SCHEMBL2527359 | 0.74 | MAPT (0.62) | MAPTKMT2ASMN1; SMN2ALDH1A1USP2 | |
| SCHEMBL26534954 | 0.73 | MAPT (0.62) | TDP1MAPTKMT2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL13196814 | 0.73 | MAPT (0.62) | TDP1MAPTKMT2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL4933314 | 0.73 | KMT2A (0.69) | TDP1MAPTKMT2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL2754053 | 0.72 | SCD (0.93) | MAPTKMT2ASMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL2406227 | 0.70 | MAPT (0.58) | MAPTKMT2ASMN1; SMN2ALDH1A1USP2 | |
| SCHEMBL4910026 | 0.70 | NPC1 (1.00) | MAPTKMT2ASMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL7944975 | 0.69 | MEN1 (0.74) | MAPTKMT2ASMN1; SMN2ALDH1A1USP2 | |
| SCHEMBL15288025 | 0.69 | MAPT (0.71) | MAPTKMT2ASMN1; SMN2ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006019586-A2 | METHOD OF TREATING TRAUMA OR SEPSIS | HAUSER CARL J (US) | 2006-02-23 | — | — | WO | disclosed |