Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.62 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.56 |
| ▸ | HPGD | P15428 | 3/20 | 0.55 |
| ▸ | LMNA | P02545 | 4/20 | 0.54 |
| ▸ | TP53 | P04637 | 1/20 | 0.54 |
| ▸ | PKM | P14618 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.54 |
| ▸ | MEN1 | O00255 | 5/20 | 0.54 |
| ▸ | POLB | P06746 | 3/20 | 0.54 |
| ▸ | RAB9A | P51151 | 3/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.52 |
| ▸ | TSHR | P16473 | 3/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.52 |
| ▸ | HTT | P42858 | 2/20 | 0.52 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26534954 | 0.78 | MAPT (0.62) | MAPTALDH1A1ENPP1HPGDLMNA | |
| SCHEMBL7944975 | 0.74 | MEN1 (0.74) | MAPTALDH1A1HPGDLMNAPKM | |
| SCHEMBL5798106 | 0.73 | TDP1 (0.60) | MAPTALDH1A1HPGDLMNATP53 | |
| SCHEMBL21663585 | 0.72 | ENPP1 (0.79) | MAPTALDH1A1ENPP1HPGDLMNA | |
| SCHEMBL30675573 | 0.72 | ENPP1 (1.00) | MAPTALDH1A1ENPP1LMNATP53 | |
| SCHEMBL20679588 | 0.72 | ENPP1 (1.00) | MAPTALDH1A1ENPP1LMNATP53 | |
| SCHEMBL15195155 | 0.71 | RAB9A (0.59) | MAPTALDH1A1HPGDLMNAPKM | |
| SCHEMBL7933388 | 0.69 | HDAC3 (0.71) | MAPTALDH1A1LMNAKMT2AMEN1 | |
| SCHEMBL2406227 | 0.69 | MAPT (0.58) | MAPTALDH1A1ENPP1LMNATP53 | |
| SCHEMBL16562029 | 0.69 | HPGD (0.78) | MAPTALDH1A1HPGDLMNATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100210836-A1 | SMALL MOLECULE INHIBITORS OF LYMPHOID TYROSINE PHOSPHATASE | UNIVERSITY OF SOUTHERN CALIFORNIA (US) | 2010-08-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100210836-A1 | SMALL MOLECULE INHIBITORS OF LYMPHOID TYROSINE PHOSPHATASE | PTPRCAP, PTPRC, PTPRA | MAPT 2762/4885ALDH1A1 2982/4885ENPP1 172/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.