Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 8/20 | 0.43 |
| ▸ | REN | P00797 | 4/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | F2 | P00734 | 1/20 | 0.35 |
| ▸ | LTA4H | P09960 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | PEPD | P12955 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.35 |
| ▸ | HRH1 | P35367 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28209840 | 0.90 | ACE (0.45) | ACERENLMNAHSD17B10CYP2C19 | |
| SCHEMBL28323878 | 0.80 | ACE (0.40) | ACERENLMNAHSD17B10CYP2C19 | |
| SCHEMBL22175770 | 0.80 | ACE (0.41) | ACERENLMNAHSD17B10CYP2C19 | |
| SCHEMBL2678393 | 0.80 | ACE (0.41) | ACERENLMNAHSD17B10CYP2C19 | |
| Water SCHEMBL11392377 | 0.79 | ACE (0.37) | ACERENLMNAHSD17B10CYP2C19 | |
| SCHEMBL11399861 | 0.78 | ACE (0.36) | ACERENLMNAHSD17B10CYP2C19 | |
| SCHEMBL27889361 | 0.76 | ACE (0.44) | ACERENLMNAHSD17B10CYP2C19 | |
| SCHEMBL5516830 | 0.75 | L3MBTL1 (0.39) | ACERENLMNAHSD17B10CYP2C19 | |
| SCHEMBL19521446 | 0.72 | ACE (0.39) | ACERENLMNAHSD17B10CYP2C19 | |
| SCHEMBL19521447 | 0.72 | ACE (0.39) | ACERENLMNAHSD17B10CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006060548-A2 | NOVEL DERMATOLOGICAL COMPOSITION USING BIO-ACTIVATING ORGANOCATALYSTS | EBERSYTES, LLC (US) | 2006-06-08 | — | — | WO | disclosed |