SCHEMBL5798442

SCHEMBL5798442

C1=Cc2cc3c(-c4ccccn4)c(-c4ccccn4)c(c(-c4ccccn4)c4nc(cc5ccc(cc1n2)[nH]5)C=C4)n3-c1ccccn1.[Mn]

nearest known ligand 0.37

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
▸ STAT3 P40763 1/20 0.37
▸ STAT1 P42224 1/20 0.37
▸ CBFB Q13951 1/20 0.30
▸ KDM4E B2RXH2 1/20 0.30
▸ NPC1 O15118 1/20 0.30
▸ LMNA P02545 1/20 0.30
▸ MAPT P10636 1/20 0.30
▸ PKM P14618 1/20 0.30
▸ RAB9A P51151 1/20 0.30
▸ KMT2A Q03164 1/20 0.30
▸ SMN1; SMN2 Q16637 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3261540 0.99 STAT3 (0.38) STAT3STAT1CBFBKDM4ENPC1
SCHEMBL28584534 0.98 STAT3 (0.37) STAT3STAT1CBFBKDM4ENPC1
SCHEMBL28399602 0.98 STAT3 (0.37) STAT3STAT1CBFBKDM4ENPC1
SCHEMBL6764274 0.98 STAT3 (0.37) STAT3STAT1CBFBKDM4ENPC1
SCHEMBL7571349 0.98 STAT3 (0.37) STAT3STAT1CBFBKDM4ENPC1
SCHEMBL5796219 0.98 STAT3 (0.37) STAT3STAT1CBFBKDM4ENPC1
SCHEMBL28752550 0.97 STAT3 (0.37) STAT3STAT1
SCHEMBL28247729 0.97 STAT3 (0.37) STAT3STAT1
SCHEMBL14080381 0.91 STAT3 (0.45) STAT3STAT1KDM4ENPC1LMNA
SCHEMBL9588222 0.90 STAT3 (0.38) STAT3STAT1CBFB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110649244-A Carbon nanotube supported tetrapyridylporphyrin manganese composite carbon electrode and roll-forming preparation method and application thereof 陕西科技大学 2020-01-03 — — CN claimed
CN-106565417-B The method that porphyrin bionic catalyst aoxidizes HBCDs synthesis OH-HBCDs 上海大学 2019-07-23 — — CN claimed
CN-106565417-A Method for synthesizing OH-HBCDs by porphyrin biomimetic catalyst oxidation of HBCDs 上海大学 2017-04-19 — — CN claimed
CN-110649244-A Carbon nanotube supported tetrapyridylporphyrin manganese composite carbon electrode and roll-forming preparation method and application thereof 陕西科技大学 2020-01-03 — — CN disclosed
CN-110649244-A Carbon nanotube supported tetrapyridylporphyrin manganese composite carbon electrode and roll-forming preparation method and application thereof 陕西科技大学 2020-01-03 — — CN disclosed
CN-106565417-B The method that porphyrin bionic catalyst aoxidizes HBCDs synthesis OH-HBCDs 上海大学 2019-07-23 — — CN disclosed
CN-106565417-A Method for synthesizing OH-HBCDs by porphyrin biomimetic catalyst oxidation of HBCDs 上海大学 2017-04-19 — — CN disclosed
WO-2006034009-A2 PURIFICATION OF BIOMOLECULES FROM CONTAMINATING INTACT NUCLEIC ACIDS SIGMA-ALDRICH CO. (US) 2006-03-30 — — WO disclosed
US-20060068430-A1 Purification of biomolecules from contaminating intact nucleic acids SIGMA-ALDRICH CO. 2006-03-30 — — US disclosed
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