Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STAT3 | P40763 | 1/20 | 0.38 |
| ▸ | STAT1 | P42224 | 1/20 | 0.38 |
| ▸ | SLC11A2 | P49281 | 1/20 | 0.35 |
| ▸ | METAP2 | P50579 | 1/20 | 0.33 |
| ▸ | METAP1 | P53582 | 1/20 | 0.33 |
| ▸ | CBFB | Q13951 | 1/20 | 0.33 |
| ▸ | TGFBR1 | P36897 | 5/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | DCTPP1 | Q9H773 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3261540 | 0.91 | STAT3 (0.38) | STAT3STAT1CBFB | |
| SCHEMBL28584534 | 0.90 | STAT3 (0.37) | STAT3STAT1METAP2METAP1CBFB | |
| SCHEMBL5798442 | 0.90 | STAT3 (0.37) | STAT3STAT1CBFB | |
| SCHEMBL7571349 | 0.90 | STAT3 (0.37) | STAT3STAT1CBFB | |
| SCHEMBL6764274 | 0.90 | STAT3 (0.37) | STAT3STAT1CBFB | |
| SCHEMBL28399602 | 0.90 | STAT3 (0.37) | STAT3STAT1CBFB | |
| SCHEMBL5796219 | 0.90 | STAT3 (0.37) | STAT3STAT1CBFB | |
| SCHEMBL28752550 | 0.89 | STAT3 (0.37) | STAT3STAT1 | |
| SCHEMBL28247729 | 0.89 | STAT3 (0.37) | STAT3STAT1 | |
| SCHEMBL14080381 | 0.87 | STAT3 (0.45) | STAT3STAT1SLC11A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5268371-A | Derivatives of porphyrin and metalloporphyrins optionally coupled to a biologically active molecule and pharmaceutical composition containing them | CIS BIO INTERNATIONAL (FR) | 1993-12-07 | — | — | US | disclosed |