Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 10/20 | 0.41 |
| ▸ | SCN5A | Q14524 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5460141 | 0.91 | KCNH2 (0.41) | KCNH2SCN5ACYP1A2CYP3A4CYP2D6 | |
| SCHEMBL5464806 | 0.85 | KCNH2 (0.41) | KCNH2SCN5A | |
| SCHEMBL5465780 | 0.85 | KCNH2 (0.45) | KCNH2SCN5A | |
| SCHEMBL5798546 | 0.85 | KCNH2 (0.44) | KCNH2SCN5ACYP1A2CYP3A4CYP2D6 | |
| SCHEMBL5461950 | 0.83 | KCNH2 (0.44) | KCNH2SCN5ACYP1A2CYP3A4CYP2D6 | |
| SCHEMBL7555397 | 0.83 | KCNH2 (0.46) | KCNH2SCN5A | |
| SCHEMBL1381414 | 0.83 | KCNH2 (0.47) | KCNH2SCN5A | |
| SCHEMBL5454203 | 0.83 | KCNH2 (0.41) | KCNH2SCN5ACYP1A2CYP3A4CYP2D6 | |
| SCHEMBL4502791 | 0.82 | KCNH2 (0.47) | KCNH2SCN5ACYP1A2CYP3A4CYP2D6 | |
| SCHEMBL5460096 | 0.81 | KCNH2 (0.43) | KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1687296-A1 | ANTIBACTERIAL AMINOQUINAZOLIDINEDIONE DERIVATIVES | Warner-Lambert Company LLC (US) | 2006-08-09 | — | — | EP | disclosed |
| WO-2005049605-A1 | ANTIBACTERIAL AMINOQUINAZOLIDINEDIONE DERIVATIVES | WARNER-LAMBERT COMPANY LLC (US) | 2005-06-02 | — | — | WO | disclosed |