Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3867297 | 0.88 | ESR2 (0.52) | PTGS2ESR2 | |
| SCHEMBL3867288 | 0.88 | ESR2 (0.52) | PTGS2ESR2 | |
| SCHEMBL3868554 | 0.88 | ESR2 (0.52) | PTGS2ESR2 | |
| SCHEMBL3868550 | 0.88 | ESR2 (0.52) | PTGS2ESR2 | |
| SCHEMBL5807999 | 0.87 | PTGS2 (0.52) | PTGS2ESR2 | |
| SCHEMBL3480155 | 0.87 | PTGS2 (0.52) | PTGS2ESR2 | |
| SCHEMBL3480153 | 0.87 | PTGS2 (0.52) | PTGS2ESR2 | |
| SCHEMBL5798485 | 0.85 | PTGS2 (0.45) | PTGS2ESR2 | |
| SCHEMBL3480364 | 0.85 | PTGS2 (0.45) | PTGS2ESR2 | |
| SCHEMBL3480365 | 0.85 | PTGS2 (0.45) | PTGS2ESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0788476-B1 | STILBENE DERIVATIVES USEFUL AS CYCLOOXYGENASE-2 INHIBITORS | MERCK FROSST CANADA INC (CA) | 1999-10-20 | — | — | EP | claimed |
| WO-2006044230-A1 | WATER SOLUBLE PRODRUGS OF COX-2 INHIBITORS | MERCK & CO., INC. (US) | 2006-04-27 | — | — | WO | disclosed |
| US-5849943-A | Stilbene derivatives useful as cyclooxygenase-2 inhibitors | MERCK FROSST CANADA, INC. (CA) | 1998-12-15 | — | — | US | disclosed |