Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5469171 | 0.82 | KDM4E (0.35) | KDM4EMEN1ALDH1A1HPGDKMT2A | |
| SCHEMBL5459818 | 0.80 | KCNH2 (0.39) | KCNH2 | |
| SCHEMBL5455435 | 0.71 | KCNH2 (0.43) | KDM4EALDH1A1HPGDHSD17B10KCNH2 | |
| SCHEMBL5460712 | 0.71 | KCNH2 (0.49) | KDM4EALDH1A1HPGDHSD17B10KCNH2 | |
| SCHEMBL5460137 | 0.71 | KCNH2 (0.43) | KDM4EALDH1A1HPGDHSD17B10KCNH2 | |
| SCHEMBL5453103 | 0.71 | KCNH2 (0.39) | KDM4EALDH1A1HPGDHSD17B10KCNH2 | |
| SCHEMBL6672872 | 0.69 | KCNH2 (0.36) | KDM4EMEN1ALDH1A1HPGDKMT2A | |
| SCHEMBL5465077 | 0.69 | KCNH2 (0.45) | KDM4EALDH1A1HPGDHSD17B10KCNH2 | |
| SCHEMBL7099308 | 0.69 | KDM4E (0.40) | KDM4EMEN1ALDH1A1HPGDKMT2A | |
| SCHEMBL5456782 | 0.69 | KCNH2 (0.34) | KDM4EMEN1ALDH1A1HPGDKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1687296-A1 | ANTIBACTERIAL AMINOQUINAZOLIDINEDIONE DERIVATIVES | Warner-Lambert Company LLC (US) | 2006-08-09 | — | — | EP | disclosed |
| WO-2005049605-A1 | ANTIBACTERIAL AMINOQUINAZOLIDINEDIONE DERIVATIVES | WARNER-LAMBERT COMPANY LLC (US) | 2005-06-02 | — | — | WO | disclosed |