Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.48 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.48 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.48 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.48 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.48 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.48 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.48 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.48 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.48 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.48 |
| ▸ | MET | P08581 | 1/20 | 0.37 |
| ▸ | FAAH | O00519 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | ABL1 | P00519 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | LEF1 | Q9UJU2 | 1/20 | 0.35 |
| ▸ | ALPL | P05186 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5799111 | 1.00 | HDAC6 (0.48) | HDAC6HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL5797318 | 0.90 | HDAC6 (0.49) | HDAC6HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL5797322 | 0.90 | HDAC6 (0.49) | HDAC6HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL5796842 | 0.89 | HDAC6 (0.62) | HDAC6HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL5797829 | 0.86 | HDAC3 (0.51) | HDAC6HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL5796586 | 0.85 | HDAC3 (0.50) | HDAC6HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL5799562 | 0.85 | FAAH (0.47) | HDAC6HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL5799753 | 0.84 | HDAC6 (0.57) | HDAC6HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL5795694 | 0.83 | MAPK1 (0.48) | HDAC6HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL5796420 | 0.82 | HDAC6 (0.38) | HDAC6HDAC3HDAC4HDAC1HDAC7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006025683-A1 | ARYLAMINOMETHYL PROPENYL BENZHYDROXYAMID DERIVATIVES WITH INHIBITORY ACTIVITY AGAINST HISTONE DEACETYLASE AND METHOD FOR THE PREPARATION THEREOF | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2006-03-09 | — | — | WO | disclosed |