Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX3 | P56373 | 2/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | HPGD | P15428 | 4/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.42 |
| ▸ | HTR1B | P28222 | 3/20 | 0.42 |
| ▸ | HTR1D | P28221 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.40 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.40 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.40 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.40 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5796084 | 0.92 | P2RX3 (0.47) | P2RX3ALDH1A1HPGDKDM4ETDP1 | |
| SCHEMBL1306876 | 0.91 | P2RX3 (0.57) | P2RX3ALDH1A1HPGDKDM4ETDP1 | |
| SCHEMBL1306879 | 0.91 | P2RX3 (0.57) | P2RX3ALDH1A1HPGDKDM4ETDP1 | |
| SCHEMBL1306873 | 0.91 | P2RX3 (0.57) | P2RX3ALDH1A1HPGDKDM4ETDP1 | |
| SCHEMBL5795713 | 0.89 | MAPT (0.46) | P2RX3ALDH1A1HPGDKDM4ETDP1 | |
| SCHEMBL1306460 | 0.84 | P2RX3 (0.56) | P2RX3ALDH1A1HPGDKDM4ETDP1 | |
| SCHEMBL1306463 | 0.84 | P2RX3 (0.56) | P2RX3ALDH1A1HPGDKDM4ETDP1 | |
| SCHEMBL1306462 | 0.84 | P2RX3 (0.56) | P2RX3ALDH1A1HPGDKDM4ETDP1 | |
| SCHEMBL1306842 | 0.83 | P2RX3 (0.54) | P2RX3ALDH1A1HPGDMAPTGAA | |
| SCHEMBL1306838 | 0.83 | P2RX3 (0.54) | P2RX3ALDH1A1HPGDMAPTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006025683-A1 | ARYLAMINOMETHYL PROPENYL BENZHYDROXYAMID DERIVATIVES WITH INHIBITORY ACTIVITY AGAINST HISTONE DEACETYLASE AND METHOD FOR THE PREPARATION THEREOF | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2006-03-09 | — | — | WO | claimed |
| WO-2006025683-A1 | ARYLAMINOMETHYL PROPENYL BENZHYDROXYAMID DERIVATIVES WITH INHIBITORY ACTIVITY AGAINST HISTONE DEACETYLASE AND METHOD FOR THE PREPARATION THEREOF | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2006-03-09 | — | — | WO | disclosed |