Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 19/20 | 0.50 |
| ▸ | PPARA | Q07869 | 18/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | PPARD | Q03181 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5799421 | 1.00 | PPARG (0.50) | PPARGPPARATP53MAPTSMN1; SMN2 | |
| SCHEMBL5813111 | 0.94 | PPARG (0.52) | PPARGPPARAPPARD | |
| SCHEMBL5813107 | 0.94 | PPARG (0.52) | PPARGPPARAPPARD | |
| SCHEMBL5802172 | 0.93 | PPARG (0.42) | PPARGPPARATP53MAPTSMN1; SMN2 | |
| SCHEMBL5802170 | 0.93 | PPARG (0.42) | PPARGPPARATP53MAPTSMN1; SMN2 | |
| SCHEMBL5799644 | 0.88 | PPARG (0.43) | PPARGPPARAMAPT | |
| SCHEMBL5799598 | 0.88 | PPARG (0.43) | PPARGPPARAMAPT | |
| SCHEMBL5822692 | 0.86 | PPARA (0.47) | PPARGPPARAPPARD | |
| SCHEMBL5822695 | 0.86 | PPARA (0.47) | PPARGPPARAPPARD | |
| SCHEMBL5314082 | 0.84 | MAPT (0.40) | PPARGPPARATP53MAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006057503-A1 | NOVEL COMPOUNDS AS AGONIST FOR PPARϜ AND PPARα, METHOD FOR PREPARATION OF THE SAME, AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME | LG LIFE SCIENCES, LTD. (KR) | 2006-06-01 | — | — | WO | claimed |
| WO-2006057503-A1 | NOVEL COMPOUNDS AS AGONIST FOR PPARϜ AND PPARα, METHOD FOR PREPARATION OF THE SAME, AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME | LG LIFE SCIENCES, LTD. (KR) | 2006-06-01 | — | — | WO | disclosed |