Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 8/20 | 0.43 |
| ▸ | PPARA | Q07869 | 7/20 | 0.43 |
| ▸ | MAPT | P10636 | 6/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.36 |
| ▸ | HAVCR2 | Q8TDQ0 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | CSGALNACT1 | Q8TDX6 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5799598 | 1.00 | PPARG (0.43) | PPARGPPARAMAPTLMNATHRB | |
| SCHEMBL5802170 | 0.95 | PPARG (0.42) | PPARGPPARAMAPTLMNAPTPN1 | |
| SCHEMBL5802172 | 0.95 | PPARG (0.42) | PPARGPPARAMAPTLMNAPTPN1 | |
| SCHEMBL5813111 | 0.93 | PPARG (0.52) | PPARGPPARA | |
| SCHEMBL5813107 | 0.93 | PPARG (0.52) | PPARGPPARA | |
| SCHEMBL5799336 | 0.88 | PPARG (0.50) | PPARGPPARAMAPT | |
| SCHEMBL5799421 | 0.88 | PPARG (0.50) | PPARGPPARAMAPT | |
| SCHEMBL5822695 | 0.84 | PPARA (0.47) | PPARGPPARAPTPN1 | |
| SCHEMBL5822692 | 0.84 | PPARA (0.47) | PPARGPPARAPTPN1 | |
| SCHEMBL5815019 | 0.81 | HAVCR2 (0.40) | PPARGPPARAHAVCR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006057503-A1 | NOVEL COMPOUNDS AS AGONIST FOR PPARϜ AND PPARα, METHOD FOR PREPARATION OF THE SAME, AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME | LG LIFE SCIENCES, LTD. (KR) | 2006-06-01 | — | — | WO | disclosed |