Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.46 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | RARB | P10826 | 1/20 | 0.42 |
| ▸ | RARG | P13631 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | TYR | P14679 | 1/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 4/20 | 0.41 |
| ▸ | NR1H4 | Q96RI1 | 3/20 | 0.41 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.41 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.41 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27885381 | 1.00 | HDAC1 (0.47) | HDAC1MEN1ALDH1A1HTTKMT2A | |
| SCHEMBL7799695 | 0.82 | NR4A1 (0.61) | ALDH1A1SRD5A2MAPTNR4A1NR4A2 | |
| SCHEMBL7804956 | 0.82 | NR4A1 (0.61) | ALDH1A1SRD5A2MAPTNR4A1NR4A2 | |
| SCHEMBL28031837 | 0.82 | HDAC1 (0.48) | HDAC1MEN1ALDH1A1HTTKMT2A | |
| SCHEMBL8160158 | 0.80 | RXRA (0.55) | MEN1ALDH1A1KMT2AMAPTRARB | |
| SCHEMBL8160160 | 0.80 | RXRA (0.55) | MEN1ALDH1A1KMT2AMAPTRARB | |
| SCHEMBL22363236 | 0.79 | HDAC1 (0.48) | HDAC1MEN1ALDH1A1HTTKMT2A | |
| SCHEMBL22363237 | 0.79 | HDAC1 (0.48) | HDAC1MEN1ALDH1A1HTTKMT2A | |
| SCHEMBL28609678 | 0.78 | HDAC1 (0.46) | HDAC1MEN1ALDH1A1HTTKMT2A | |
| SCHEMBL13676268 | 0.78 | HDAC1 (0.46) | HDAC1MEN1ALDH1A1HTTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109369365-A | A kind of lilial intermediate is to tert-butyl-α-methylcinnamaldehyde preparation method | 山东新和成药业有限公司 | 2019-02-22 | — | — | CN | claimed |
| CN-117247977-A | Method for synthesizing convaldehyde by enzyme method | 四川大学 | 2023-12-19 | — | — | CN | disclosed |
| CN-109369365-A | A kind of lilial intermediate is to tert-butyl-α-methylcinnamaldehyde preparation method | 山东新和成药业有限公司 | 2019-02-22 | — | — | CN | disclosed |
| CN-109369365-A | A kind of lilial intermediate is to tert-butyl-α-methylcinnamaldehyde preparation method | 山东新和成药业有限公司 | 2019-02-22 | — | — | CN | disclosed |
| CN-109369365-A | A kind of lilial intermediate is to tert-butyl-α-methylcinnamaldehyde preparation method | 山东新和成药业有限公司 | 2019-02-22 | — | — | CN | disclosed |
| CN-102413908-B | The method of conditioning catalysts by membrane filtration | BASF SE (DE) | 2015-09-23 | — | — | CN | disclosed |
| CN-102413908-A | Method for conditioning catalysts by membrane filtration | BASF SE | 2012-04-11 | — | — | CN | disclosed |
| WO-2006033795-A2 | SUBSTITUTED PYRAZOLO [1, 5-A] PYRIMIDINES FOR INHIBITING ABNORMAL CELL GROWTH | WYETH (US) | 2006-03-30 | — | — | WO | disclosed |
| WO-2006033796-A1 | SUBSTITUTED PYRAZOLO [1,5-a] PYRIMIDINES AND PROCESS FOR MAKING SAME | WYETH (US) | 2006-03-30 | — | — | WO | disclosed |
| US-20060063784-A1 | Method of using substituted pyrazolo [1,5-a] pyrimidines | WYETH | 2006-03-23 | — | — | US | disclosed |
| US-20060063785-A1 | Substituted pyrazolo[1,5-a] pyrimidines and process for making same | WYETH | 2006-03-23 | — | — | US | disclosed |
| EP-0802897-A1 | NOVEL COMPOUNDS | Smithkline Beecham S.p.A. (IT) | 1997-10-29 | — | — | EP | disclosed |
| WO-1996021638-A1 | NOVEL COMPOUNDS | SMITHKLINE BEECHAM S.P.A. (IT) | 1996-07-18 | — | — | WO | disclosed |
| US-4283534-A | Reductive alkylation of nitrogen heterocycles | BASF AKTIENGESELLSCHAFT (DE) | 1981-08-11 | — | — | US | disclosed |
| US-4263459-A | 3-Methyl-aldehydes, processes for their preparation and their use as odorants | HAARMANN & REIMER GMBH (DE) | 1981-04-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060063785-A1 | Substituted pyrazolo[1,5-a] pyrimidines and process for making same | TYMP, DPYD, TYMS | HDAC1 2680/4885MEN1 2019/4885ALDH1A1 848/4885 |
| US-20060063784-A1 | Method of using substituted pyrazolo [1,5-a] pyrimidines | TYMP, DPYD, TYMS | HDAC1 1859/4885MEN1 2653/4885ALDH1A1 847/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.