Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 1/20 | 0.41 |
| ▸ | ACACA | Q13085 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 4/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.38 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.36 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.36 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.36 |
| ▸ | CYP2J2 | P51589 | 1/20 | 0.36 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.36 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.35 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.35 |
| ▸ | PTGES | O14684 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL198568 | 0.87 | NR3C1 (0.36) | ACACBACACANR3C1ADRB2ADRB1 | |
| SCHEMBL12926311 | 0.87 | MAOB (0.48) | ACACBACACAMAOBHRH3NR3C1 | |
| SCHEMBL1338713 | 0.80 | NR3C1 (0.44) | ACACBACACAMAOBHRH3NR3C1 | |
| SCHEMBL322449 | 0.79 | ERN1 (0.44) | MAOBHRH3 | |
| SCHEMBL13317341 | 0.79 | ACACB (0.43) | ACACBACACAMAOBHRH3NPC1 | |
| SCHEMBL14274245 | 0.79 | TAAR1 (0.46) | ACACBACACAMAOBHRH3NR3C1 | |
| SCHEMBL12736261 | 0.79 | ACACB (0.43) | ACACBACACAMAOBHRH3NPC1 | |
| SCHEMBL12736281 | 0.79 | TAAR1 (0.46) | ACACBACACAMAOBHRH3NR3C1 | |
| SCHEMBL11103639 | 0.79 | KCNH2 (0.48) | ACACBACACAMAOBLMNAKCNH2 | |
| SCHEMBL9269074 | 0.78 | MAOB (0.53) | ACACBACACAMAOBHRH3KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006033995-A2 | THIAZOLIDIN-4-ONES HAVING ANTI-HEPATITIS B ACTIVITY | VALEANT RESEARCH AND DEVELOPMENT (US) | 2006-03-30 | — | — | WO | disclosed |