Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RECQL | P46063 | 2/20 | 0.71 |
| ▸ | MAPT | P10636 | 10/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.69 |
| ▸ | HTT | P42858 | 4/20 | 0.69 |
| ▸ | GAA | P10253 | 3/20 | 0.69 |
| ▸ | HPGD | P15428 | 3/20 | 0.69 |
| ▸ | RAB9A | P51151 | 4/20 | 0.61 |
| ▸ | LMNA | P02545 | 3/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.54 |
| ▸ | POLB | P06746 | 3/20 | 0.54 |
| ▸ | NPC1 | O15118 | 2/20 | 0.54 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.53 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | P4HB | P07237 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22449502 | 1.00 | RECQL (0.71) | RECQLMAPTALDH1A1HTTGAA | |
| SCHEMBL5946453 | 0.93 | MAPT (0.77) | RECQLMAPTALDH1A1HTTGAA | |
| SCHEMBL2944257 | 0.85 | MAPT (0.67) | RECQLMAPTALDH1A1HTTGAA | |
| SCHEMBL10291821 | 0.85 | MAPT (0.67) | RECQLMAPTALDH1A1HTTGAA | |
| SCHEMBL425338 | 0.83 | RECQL (1.00) | RECQLMAPTALDH1A1HTTGAA | |
| SCHEMBL446006 | 0.83 | RECQL (1.00) | RECQLMAPTALDH1A1HTTGAA | |
| SCHEMBL29176317 | 0.83 | RECQL (1.00) | RECQLMAPTALDH1A1HTTGAA | |
| SCHEMBL5646420 | 0.83 | MAPT (0.69) | RECQLMAPTALDH1A1HTTGAA | |
| SCHEMBL2945499 | 0.83 | MAPT (0.69) | RECQLMAPTALDH1A1HTTGAA | |
| SCHEMBL9728821 | 0.83 | MAPT (0.69) | RECQLMAPTALDH1A1HTTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110407833-B | Deuterated Vissturtib compound and application thereof | 海创药业股份有限公司 | 2021-03-09 | — | — | CN | disclosed |
| WO-2006033795-A2 | SUBSTITUTED PYRAZOLO [1, 5-A] PYRIMIDINES FOR INHIBITING ABNORMAL CELL GROWTH | WYETH (US) | 2006-03-30 | — | — | WO | disclosed |
| WO-2006033796-A1 | SUBSTITUTED PYRAZOLO [1,5-a] PYRIMIDINES AND PROCESS FOR MAKING SAME | WYETH (US) | 2006-03-30 | — | — | WO | disclosed |