Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CPT1A | P50416 | 5/20 | 0.46 |
| ▸ | CPT2 | P23786 | 3/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5303450 | 0.92 | CPT1A (0.52) | CPT1ACPT2POLB | |
| SCHEMBL5303447 | 0.92 | CPT1A (0.52) | CPT1ACPT2POLB | |
| SCHEMBL2894182 | 0.90 | POLB (0.49) | CPT1ACPT2POLB | |
| SCHEMBL2894183 | 0.90 | POLB (0.49) | CPT1ACPT2POLB | |
| SCHEMBL5314047 | 0.83 | CPT1A (0.52) | CPT1ACPT2 | |
| SCHEMBL3963483 | 0.82 | CPT1A (0.52) | CPT1ACPT2 | |
| SCHEMBL4059432 | 0.82 | CPT1A (0.52) | CPT1ACPT2 | |
| SCHEMBL5784886 | 0.82 | POLB (0.37) | POLB | |
| SCHEMBL3966278 | 0.82 | CPT1A (0.52) | CPT1ACPT2 | |
| SCHEMBL3962625 | 0.82 | CPT1A (0.52) | CPT1ACPT2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1716143-A1 | POLYHETEROCYCLIC COMPOUNDS AND THEIR USE AS METABOTROPIC GLUTAMATE RECEPTOR ANTAGONISTS | AstraZeneca AB (SE) | 2006-11-02 | — | — | EP | disclosed |
| WO-2005080386-A1 | POLYHETEROCYCLIC COMPOUNDS AND THEIR USE AS METABOTROPIC GLUTAMATE RECEPTOR ANTAGONISTS | ASTRAZENECA AB (US) | 2005-09-01 | — | — | WO | disclosed |