Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 7/20 | 0.40 |
| ▸ | CNR1 | P21554 | 1/20 | 0.39 |
| ▸ | CNR2 | P34972 | 1/20 | 0.39 |
| ▸ | ELANE | P08246 | 1/20 | 0.39 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.36 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.36 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.36 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.36 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.36 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | MGLL | Q99685 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5800746 | 1.00 | PTGS2 (0.40) | PTGS2CNR1CNR2ELANEPSEN1 | |
| SCHEMBL5797723 | 0.95 | ELANE (0.40) | PTGS2CNR1CNR2ELANEKMT2A | |
| SCHEMBL5797729 | 0.95 | ELANE (0.40) | PTGS2CNR1CNR2ELANEKMT2A | |
| SCHEMBL5558888 | 0.92 | ELANE (0.44) | CNR1CNR2ELANEPSEN1PSEN2 | |
| SCHEMBL5558886 | 0.92 | ELANE (0.44) | CNR1CNR2ELANEPSEN1PSEN2 | |
| SCHEMBL5798223 | 0.90 | PTGS2 (0.49) | PTGS2 | |
| SCHEMBL5798225 | 0.90 | PTGS2 (0.49) | PTGS2 | |
| SCHEMBL5813475 | 0.89 | PTGS2 (0.40) | PTGS2 | |
| SCHEMBL6425681 | 0.89 | PTGS2 (0.40) | PTGS2 | |
| SCHEMBL5813479 | 0.89 | PTGS2 (0.40) | PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006050120-A2 | SYNTHESIS OF COX-2 AND FAAH INHIBITORS | MICROBIA, INC. (US) | 2006-05-11 | — | — | WO | disclosed |