SCHEMBL5800775

SCHEMBL5800775

O=CC1=CCC(=Cc2ccccc2)C=C1c1ccccc1

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.35
CYP2A6 P11509 1/20 0.35
CYP1A2 P05177 2/20 0.33
TRPA1 O75762 1/20 0.32
LMNA P02545 1/20 0.32
ALOX5 P09917 1/20 0.32
MAPK1 P28482 1/20 0.32
BACE1 P56817 2/20 0.31
PTPRC P08575 1/20 0.31
PTPRF P10586 1/20 0.31
PTPN1 P18031 1/20 0.31
CDC25B P30305 1/20 0.31
F3 P13726 1/20 0.31
MEN1 O00255 2/20 0.31
KMT2A Q03164 2/20 0.31
NPC1 O15118 1/20 0.31
TRIM24 O15164 1/20 0.30
TRIM33 Q9UPN9 1/20 0.30
MAPT P10636 1/20 0.30
HTT P42858 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11034797 0.64 CYP1A2 (0.33) ALDH1A1CYP1A2LMNACDC25BF3
SCHEMBL28066368 0.62 CYP1A2 (0.44) ALDH1A1CYP2A6CYP1A2LMNAPTPN1
SCHEMBL28720861 0.60 BACE1 (0.57) ALDH1A1CYP1A2LMNABACE1PTPRC
Biphenyl SCHEMBL2390667 0.60 ALDH1A1 (0.82) ALDH1A1CYP2A6TRPA1LMNAALOX5
Benzaldehyde SCHEMBL27714136 0.59
Benzaldehyde SCHEMBL29264731 0.59 ALDH1A1 (0.93) ALDH1A1CYP2A6TRPA1LMNAALOX5
Benzaldehyde SCHEMBL28825780 0.58 ALDH1A1 (0.78) ALDH1A1CYP2A6TRPA1LMNAALOX5
Tannin Pyrogallol SCHEMBL28663913 0.58 ALDH1A1 (0.78) ALDH1A1CYP2A6CYP1A2TRPA1LMNA
Benzaldehyde SCHEMBL10325507 0.57 ALDH1A1 (0.74) ALDH1A1CYP2A6TRPA1LMNAALOX5
Benzaldehyde SCHEMBL9236967 0.57

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2006044626-A2 THERMOPLASTIC ARTICLES FOR PACKAGING UV SENSITIVE MATERIALS, PROCESSES FOR THE ARTICLES PRODUCTION AND USE AND NOVEL UV ABSORBERS COLORCHEM INTERNATIONAL CORPORATION (US) 2006-04-27 WO disclosed