Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | MGLL | Q99685 | 1/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 8/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.35 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.34 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.34 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.34 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.34 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.34 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.34 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.34 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.33 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5800816 | 1.00 | TSHR (0.40) | TSHRMGLLPTGS2PTGS1AKR1C3 | |
| SCHEMBL5797101 | 0.93 | PTGS2 (0.38) | TSHRMGLLPTGS2PTGS1AKR1C3 | |
| SCHEMBL5797104 | 0.93 | PTGS2 (0.38) | TSHRMGLLPTGS2PTGS1AKR1C3 | |
| SCHEMBL5798119 | 0.92 | PTGS2 (0.40) | TSHRPTGS2 | |
| SCHEMBL5798122 | 0.92 | PTGS2 (0.40) | TSHRPTGS2 | |
| SCHEMBL5797301 | 0.90 | PTGS2 (0.36) | TSHRPTGS2PTGS1AKR1C3AKR1C2 | |
| SCHEMBL5797307 | 0.90 | PTGS2 (0.36) | TSHRPTGS2PTGS1AKR1C3AKR1C2 | |
| SCHEMBL5814349 | 0.90 | PTGS2 (0.45) | PTGS2PTGS1AKR1C3AKR1C2ABCB1 | |
| SCHEMBL5814350 | 0.90 | PTGS2 (0.45) | PTGS2PTGS1AKR1C3AKR1C2ABCB1 | |
| SCHEMBL5797453 | 0.89 | APP (0.37) | TSHRPTGS2PTGS1AKR1C3AKR1C2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006050120-A2 | SYNTHESIS OF COX-2 AND FAAH INHIBITORS | MICROBIA, INC. (US) | 2006-05-11 | — | — | WO | disclosed |