Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 1/20 | 0.36 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.36 |
| ▸ | SRC | P12931 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | LMNA | P02545 | 3/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | HPGD | P15428 | 3/20 | 0.34 |
| ▸ | HTT | P42858 | 3/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | ELANE | P08246 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6422490 | 0.93 | ELANE (0.37) | AKR1C3AKR1C2SRCKDM4ELMNA | |
| SCHEMBL6422491 | 0.93 | ELANE (0.37) | AKR1C3AKR1C2SRCKDM4ELMNA | |
| SCHEMBL5800476 | 0.91 | PTGS2 (0.37) | SRCMAPTELANEPTGS2CXCL8 | |
| SCHEMBL6423746 | 0.91 | AKR1C3 (0.39) | AKR1C3AKR1C2SRCKDM4ELMNA | |
| SCHEMBL6423736 | 0.91 | AKR1C3 (0.39) | AKR1C3AKR1C2SRCKDM4ELMNA | |
| SCHEMBL5813354 | 0.90 | PTGS2 (0.37) | AKR1C3AKR1C2SRCCYP2D6PTGS2 | |
| SCHEMBL5798836 | 0.89 | AKR1C3 (0.40) | AKR1C3AKR1C2SRCKDM4ELMNA | |
| SCHEMBL5798826 | 0.89 | AKR1C3 (0.40) | AKR1C3AKR1C2SRCKDM4ELMNA | |
| SCHEMBL5798830 | 0.89 | AKR1C3 (0.40) | AKR1C3AKR1C2SRCKDM4ELMNA | |
| SCHEMBL5800851 | 0.89 | PTGS2 (0.37) | AKR1C3AKR1C2SRCMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006050120-A2 | SYNTHESIS OF COX-2 AND FAAH INHIBITORS | MICROBIA, INC. (US) | 2006-05-11 | — | — | WO | disclosed |