Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 7/20 | 0.37 |
| ▸ | S1PR3 | Q99500 | 7/20 | 0.37 |
| ▸ | S1PR4 | O95977 | 5/20 | 0.37 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.37 |
| ▸ | S1PR2 | O95136 | 5/20 | 0.34 |
| ▸ | CCR2 | P41597 | 2/20 | 0.33 |
| ▸ | SPHK1 | Q9NYA1 | 7/20 | 0.33 |
| ▸ | PLK1 | P53350 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | SPHK2 | Q9NRA0 | 1/20 | 0.32 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.32 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4294299 | 0.90 | CNR2 (0.35) | S1PR1S1PR3S1PR4S1PR5 | |
| SCHEMBL4290777 | 0.89 | S1PR1 (0.44) | S1PR1S1PR3S1PR4S1PR5S1PR2 | |
| SCHEMBL5794199 | 0.87 | S1PR1 (0.46) | S1PR1S1PR3S1PR4S1PR5S1PR2 | |
| SCHEMBL4300355 | 0.87 | S1PR1 (0.46) | S1PR1S1PR3S1PR4S1PR5S1PR2 | |
| SCHEMBL4288232 | 0.87 | S1PR1 (0.46) | S1PR1S1PR3S1PR4S1PR5S1PR2 | |
| SCHEMBL4296372 | 0.86 | CNR2 (0.37) | S1PR1S1PR3S1PR4S1PR5 | |
| Hydrochloric Acid SCHEMBL4288231 | 0.86 | S1PR1 (0.45) | S1PR1S1PR3S1PR4S1PR5S1PR2 | |
| SCHEMBL5795055 | 0.86 | SPHK1 (0.37) | CCR2SPHK1POLBPKMLMNA | |
| SCHEMBL5795112 | 0.85 | S1PR1 (0.36) | S1PR1S1PR3S1PR4S1PR5S1PR2 | |
| SCHEMBL5796623 | 0.85 | S1PR1 (0.38) | S1PR1S1PR3S1PR4S1PR5S1PR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006043149-A9 | NOVEL DICARBOXYLIC ACID DERIVATIVES | BIOPROJET SOC CIV (FR) | 2006-08-10 | — | — | WO | disclosed |