Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F7 | P08709 | 1/20 | 0.55 |
| ▸ | F3 | P13726 | 1/20 | 0.55 |
| ▸ | SARM1 | Q6SZW1 | 1/20 | 0.55 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.55 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.55 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.55 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.55 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.55 |
| ▸ | SIRT4 | Q9Y6E7 | 1/20 | 0.55 |
| ▸ | CPT2 | P23786 | 1/20 | 0.53 |
| ▸ | ACLY | P53396 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | APP | P05067 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.42 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.42 |
| ▸ | PLOD2 | O00469 | 1/20 | 0.40 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.40 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Niacin SCHEMBL811549 | 0.90 | ALDH1A1 (0.55) | F7F3SARM1SIRT2SIRT6 | |
| Niacinamide SCHEMBL6918787 | 0.87 | F7 (0.44) | F7F3SARM1SIRT2SIRT6 | |
| Niacinamide SCHEMBL31098926 | 0.84 | F7 (0.51) | F7F3SARM1SIRT2SIRT6 | |
| Citric Acid SCHEMBL5352836 | 0.81 | F7 (0.65) | F7F3SARM1SIRT2SIRT6 | |
| SCHEMBL21247055 | 0.78 | ALDH1A1 (0.45) | F7F3SARM1SIRT2SIRT6 | |
| Niacin SCHEMBL5465552 | 0.77 | ALDH1A1 (0.49) | CPT2ACLYALDH1A1APPGAA | |
| Cadaverine Tartrate SCHEMBL29103712 | 0.76 | F7 (0.76) | F7F3SARM1SIRT2SIRT6 | |
| Cadaverine Tartrate SCHEMBL27679158 | 0.76 | F7 (0.76) | F7F3SARM1SIRT2SIRT6 | |
| Niacinamide SCHEMBL580180 | 0.76 | F7 (0.65) | F7F3SARM1SIRT2SIRT6 | |
| Niacinamide SCHEMBL29011862 | 0.76 | F7 (0.65) | F7F3SARM1SIRT2SIRT6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 106 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070031526-A1 | Topical Deodorant Compositions Based on Hydroxycitric Acid | BIODERM RESEARCH (US) | 2007-02-08 | — | — | US | claimed |
| US-20040156873-A1 | Topically Bioavailable Acne and Rosacea Treatment Compositions | GUPTA SHYAM K (US) | 2004-08-12 | — | — | US | claimed |
| US-20040081672-A1 | Niacinamide, niacin, and niacin esters based delivery systems for treating topical disorders of skin and skin aging | GUPTA SHYAM K (US) | 2004-04-29 | — | — | US | claimed |
| CN-118302145-A | Cosmetic water-in-oil emulsion comprising a specific water-soluble UV screening agent, a base, a volatile oil, a hydrophobic film-forming polymer, a polyoxyalkylene-alkylated linear polydimethylsiloxane and vitamin B3 | 莱雅公司 | 2024-07-05 | — | — | CN | disclosed |
| WO-2024133260-A1 | PULMONARY DELIVERY DEVICES | TWENTY SIXTEEN (2016) PHARMA LIMITED (GB) | 2024-06-27 | — | — | WO | disclosed |
| EP-4370092-A2 | A NON-THERAPEUTIC COSMETIC METHOD FOR REDUCING WRINKLES ON A SKIN SURFACE | L'OREAL (FR) | 2024-05-22 | — | — | EP | disclosed |
| US-20240100265-A1 | PULMONARY DELIVERY DEVICES | TWENTY SIXTEEN (2016) PHARMA LIMITED (GB) | 2024-03-28 | — | — | US | disclosed |
| CN-117355289-A | Non-therapeutic cosmetic method for reducing wrinkles on the surface of the skin | 莱雅公司 | 2024-01-05 | — | — | CN | disclosed |
| US-20230405243-A1 | PULMONARY DELIVERY DEVICES | TWENTY SIXTEEN 2016 PHARMA LTD (GB) | 2023-12-21 | — | — | US | disclosed |
| WO-2023119230-A1 | COAGULATION PATHWAY AND NICOTINAMIDE-ADENINE DINUCLEOTIDE PATHWAY MODULATING COMPOSITIONS AND METHODS OF THEIR USE | L'OREAL (FR) | 2023-06-29 | — | — | WO | disclosed |
| WO-2023094277-A1 | COSMETIC WATER-IN-OIL EMULSION COMPRISING A SPECIFIC WATER-SOLUBLE UV SCREENING AGENT, A BASE, A VOLATILE OIL, A HYDROPHOBIC FILM-FORMING POLYMER, A POLYOXYALKYLENATED LINEAR POLYDIMETHYLMETHYLSILOXANE AND A VITAMIN B3 | L'OREAL (FR) | 2023-06-01 | — | — | WO | disclosed |
| US-20060147508-A1 | Concurrent Enhancement of Skin Penetration of Organic Base Active Agents and Organic Hydroxy Acid Active Agents as Their Ion-Pair Complexes | BIODERM RESEARCH (US) | 2006-07-06 | — | — | US | disclosed |
| US-20060110415-A1 | Topical Delivery System for Cosmetic and Pharmaceutical Agents | BIODERM RESEARCH (US) | 2006-05-25 | — | — | US | disclosed |
| US-20060074108-A1 | Matrix metalloprotease (MMP) inhibitors and their application in cosmetic and pharmaceutical composition | BIODERM RESEARCH (US) | 2006-04-06 | — | — | US | disclosed |
| WO-2006023710-A2 | COSMETIC OR PHARMACEUTICAL COMPOSITION FOR SKIN CARE | INFINITY2 HEALTH SCIENCES, INC. (US) | 2006-03-02 | — | — | WO | disclosed |
| US-20060039887-A1 | Cosmetic or pharmaceutical composition for skin care | INFINITY2 HEALTH SCIENCES, INC. | 2006-02-23 | — | — | US | disclosed |
| WO-2005123101-A1 | BLACKBERRY EXTRACT | SYMRISE GMBH & CO. KG (DE) | 2005-12-29 | — | — | WO | disclosed |
| US-20040228884-A1 | Ion-pair delivery system for cosmetic and pharmaceutical compositions | GUPTA SHYAM K (US) | 2004-11-18 | — | — | US | disclosed |
| US-20040185069-A1 | Hydroxycitric acid derivatives for body slimming and tone firming compositions | GUPTA SHYAM K (US) | 2004-09-23 | — | — | US | disclosed |
| US-20040081672-A1 | Niacinamide, niacin, and niacin esters based delivery systems for treating topical disorders of skin and skin aging | GUPTA SHYAM K (US) | 2004-04-29 | — | — | US | disclosed |