Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 15/20 | 0.47 |
| ▸ | PTGS1 | P23219 | 4/20 | 0.44 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.44 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.42 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.41 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA4 | P22748 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5553932 | 0.97 | PTGS2 (0.49) | PTGS2PTGS1HRH4HDAC3HDAC1 | |
| SCHEMBL5554002 | 0.96 | PTGS2 (0.47) | PTGS2PTGS1HRH4AKR1C3AKR1C2 | |
| SCHEMBL5558957 | 0.92 | PTGS2 (0.53) | PTGS2PTGS1HRH4HDAC3HDAC1 | |
| SCHEMBL5561166 | 0.91 | PTGS2 (0.56) | PTGS2PTGS1HRH4HDAC3HDAC1 | |
| SCHEMBL5800141 | 0.89 | PTGS2 (0.46) | PTGS2PTGS1HRH4HDAC3HDAC1 | |
| SCHEMBL5558356 | 0.89 | PTGS2 (0.46) | PTGS2PTGS1HRH4HDAC3HDAC1 | |
| SCHEMBL5797712 | 0.87 | PTGS2 (0.49) | PTGS2PTGS1HRH4HDAC3HDAC1 | |
| SCHEMBL5553844 | 0.87 | PTGS2 (0.49) | PTGS2PTGS1HRH4AKR1C3AKR1C2 | |
| SCHEMBL6462140 | 0.87 | PTGS2 (0.38) | PTGS2PTGS1HRH4AKR1C3AKR1C2 | |
| SCHEMBL6427040 | 0.87 | PTGS2 (0.53) | PTGS2PTGS1AKR1C3AKR1C2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006050120-A2 | SYNTHESIS OF COX-2 AND FAAH INHIBITORS | MICROBIA, INC. (US) | 2006-05-11 | — | — | WO | disclosed |