Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 5/20 | 0.52 |
| ▸ | AKR1C2 | P52895 | 4/20 | 0.52 |
| ▸ | PTGS2 | P35354 | 14/20 | 0.47 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5559515 | 0.94 | AKR1C3 (0.57) | AKR1C3AKR1C2PTGS2PTGS1 | |
| SCHEMBL5559089 | 0.93 | AKR1C3 (0.57) | AKR1C3AKR1C2PTGS2PTGS1 | |
| SCHEMBL5801187 | 0.89 | AKR1C3 (0.51) | AKR1C3AKR1C2PTGS2PTGS1 | |
| SCHEMBL5554627 | 0.87 | AKR1C3 (0.59) | AKR1C3AKR1C2PTGS2PTGS1 | |
| SCHEMBL5801344 | 0.86 | PTGS2 (0.53) | AKR1C3AKR1C2PTGS2 | |
| SCHEMBL5801353 | 0.86 | PTGS2 (0.54) | AKR1C3AKR1C2PTGS2PTGS1 | |
| SCHEMBL5560594 | 0.86 | AKR1C3 (0.56) | AKR1C3AKR1C2PTGS2PTGS1 | |
| SCHEMBL5558872 | 0.86 | PTGS2 (0.61) | AKR1C3AKR1C2PTGS2PTGS1 | |
| SCHEMBL5553946 | 0.86 | PPARG (0.51) | AKR1C3AKR1C2PTGS2PTGS1 | |
| SCHEMBL5559474 | 0.85 | AKR1C3 (0.52) | AKR1C3AKR1C2PTGS2PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006050120-A2 | SYNTHESIS OF COX-2 AND FAAH INHIBITORS | MICROBIA, INC. (US) | 2006-05-11 | — | — | WO | disclosed |