Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 11/20 | 0.61 |
| ▸ | NPC1 | O15118 | 3/20 | 0.61 |
| ▸ | RAB9A | P51151 | 3/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.61 |
| ▸ | CASR | P41180 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.58 |
| ▸ | F10 | P00742 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5801135 | 0.85 | CNR1 (0.57) | CNR1NPC1RAB9ASMN1; SMN2CASR | |
| SCHEMBL5802784 | 0.84 | ABAT (0.64) | NPC1RAB9ASMN1; SMN2KMT2AALDH1A1 | |
| SCHEMBL21698113 | 0.84 | CNR1 (0.54) | CNR1NPC1RAB9ASMN1; SMN2CASR | |
| SCHEMBL6374092 | 0.83 | CNR1 (0.60) | CNR1NPC1RAB9ASMN1; SMN2CASR | |
| SCHEMBL4058363 | 0.83 | NPC1 (0.65) | CNR1NPC1RAB9ASMN1; SMN2CASR | |
| SCHEMBL4105004 | 0.82 | CNR1 (0.74) | CNR1NPC1RAB9ASMN1; SMN2KMT2A | |
| SCHEMBL11054644 | 0.82 | CNR1 (0.74) | CNR1NPC1RAB9ASMN1; SMN2KMT2A | |
| SCHEMBL8264501 | 0.81 | F10 (0.55) | CNR1NPC1RAB9ASMN1; SMN2CASR | |
| SCHEMBL7951914 | 0.81 | RECQL (0.63) | SMN1; SMN2KMT2AALDH1A1 | |
| SCHEMBL11432180 | 0.80 | EPHX1 (0.57) | NPC1RAB9ASMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006063113-A2 | UREAS AS FACTOR XA INHIBITORS | PORTOLA PHARMACEUTICALS, INC. (US) | 2006-06-15 | — | — | WO | claimed |
| WO-2006063113-A2 | UREAS AS FACTOR XA INHIBITORS | PORTOLA PHARMACEUTICALS, INC. (US) | 2006-06-15 | — | — | WO | disclosed |