Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.35 |
| ▸ | THPO | P40225 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.34 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.34 |
| ▸ | TLR2 | O60603 | 1/20 | 0.31 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | CA3 | P07451 | 1/20 | 0.31 |
| ▸ | CA4 | P22748 | 1/20 | 0.31 |
| ▸ | CA6 | P23280 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5801290 | 1.00 | MAPT (0.35) | MAPTKDM4ETHRBALOX15NFKB1 | |
| SCHEMBL9966095 | 0.84 | KDM4E (0.38) | MAPTKDM4ETHRBALOX15NFKB1 | |
| SCHEMBL5656969 | 0.84 | KDM4E (0.38) | MAPTKDM4ETHRBALOX15NFKB1 | |
| SCHEMBL6470507 | 0.84 | KDM4E (0.38) | MAPTKDM4ETHRBALOX15NFKB1 | |
| SCHEMBL82152 | 0.82 | MAPT (0.50) | MAPTKDM4ETHRBALOX15NFKB1 | |
| SCHEMBL82150 | 0.82 | MAPT (0.50) | MAPTKDM4ETHRBALOX15NFKB1 | |
| SCHEMBL2408947 | 0.80 | ITGB1 (0.48) | MAPTKDM4ETHRBALOX15NFKB1 | |
| SCHEMBL8739588 | 0.80 | GAA (0.42) | MAPTKDM4ETHRBALOX15NFKB1 | |
| SCHEMBL2872923 | 0.80 | ITGB1 (0.48) | MAPTKDM4ETHRBALOX15NFKB1 | |
| SCHEMBL9688310 | 0.80 | GAA (0.42) | MAPTKDM4ETHRBALOX15NFKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006056233-A1 | PROCESS FOR THE PREPARATION OF S-CARBAMOYL CYSTEINE DERIVATIVES | PROTERA S.R.L. (IT) | 2006-06-01 | — | — | WO | disclosed |