Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.38 |
| ▸ | THPO | P40225 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.36 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA3 | P07451 | 1/20 | 0.33 |
| ▸ | CA4 | P22748 | 1/20 | 0.33 |
| ▸ | CA6 | P23280 | 1/20 | 0.33 |
| ▸ | CA5A | P35218 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6470507 | 1.00 | KDM4E (0.38) | KDM4EMAPTTHRBALOX15NFKB1 | |
| SCHEMBL9966095 | 1.00 | KDM4E (0.38) | KDM4EMAPTTHRBALOX15NFKB1 | |
| SCHEMBL2294810 | 0.85 | CYP1A2 (0.42) | KDM4EMAPTTHRBALOX15NFKB1 | |
| SCHEMBL4879818 | 0.85 | CYP1A2 (0.42) | KDM4EMAPTTHRBALOX15NFKB1 | |
| SCHEMBL8739588 | 0.84 | GAA (0.42) | KDM4EMAPTTHRBALOX15NFKB1 | |
| SCHEMBL2872923 | 0.84 | ITGB1 (0.48) | KDM4EMAPTTHRBALOX15NFKB1 | |
| SCHEMBL2873174 | 0.84 | ITGB1 (0.48) | KDM4EMAPTTHRBALOX15NFKB1 | |
| SCHEMBL2408947 | 0.84 | ITGB1 (0.48) | KDM4EMAPTTHRBALOX15NFKB1 | |
| SCHEMBL9688310 | 0.84 | GAA (0.42) | KDM4EMAPTTHRBALOX15NFKB1 | |
| SCHEMBL5801290 | 0.84 | MAPT (0.35) | KDM4EMAPTTHRBALOX15NFKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12350250-B2 | Aggrelytes for treating ocular conditions | THE REGENT OF THE UNIVERSITY OF COLORADO, A BODY CORPORATE (US) | 2025-07-08 | — | — | US | claimed |
| US-20240115538-A1 | AGGRELYTES FOR TREATING OCULAR CONDITIONS | THE REGENTS OF THE UNIVERSITY OF COLORADO, A BODY CORPORATE | 2024-04-11 | — | — | US | claimed |
| US-20250332135-A1 | Aggrelytes for Treating Ocular Conditions | UNIV COLORADO REGENTS (US) | 2025-10-30 | — | — | US | disclosed |
| US-20250332135-A1 | Aggrelytes for Treating Ocular Conditions | UNIV COLORADO REGENTS (US) | 2025-10-30 | — | — | US | disclosed |
| US-12350250-B2 | Aggrelytes for treating ocular conditions | THE REGENT OF THE UNIVERSITY OF COLORADO, A BODY CORPORATE (US) | 2025-07-08 | — | — | US | disclosed |
| US-12350250-B2 | Aggrelytes for treating ocular conditions | THE REGENT OF THE UNIVERSITY OF COLORADO, A BODY CORPORATE (US) | 2025-07-08 | — | — | US | disclosed |
| US-20240115538-A1 | AGGRELYTES FOR TREATING OCULAR CONDITIONS | THE REGENTS OF THE UNIVERSITY OF COLORADO, A BODY CORPORATE | 2024-04-11 | — | — | US | disclosed |
| US-20240115538-A1 | AGGRELYTES FOR TREATING OCULAR CONDITIONS | THE REGENTS OF THE UNIVERSITY OF COLORADO, A BODY CORPORATE | 2024-04-11 | — | — | US | disclosed |
| US-20120046232-A1 | COMPOSITIONS AND METHODS FOR REDUCING RELAPSE OF ADDICTIVE BEHAVIOR | MEDICAL UNIVERSITY OF SOUTH CAROLINA | 2012-02-23 | — | — | US | disclosed |
| US-20120046232-A1 | COMPOSITIONS AND METHODS FOR REDUCING RELAPSE OF ADDICTIVE BEHAVIOR | MEDICAL UNIVERSITY OF SOUTH CAROLINA | 2012-02-23 | — | — | US | disclosed |
| US-20060251597-A1 | ANTI-ODOR COMPOSITIONS AND THERAPEUTIC USE | YU RUEY J | 2006-11-09 | — | — | US | disclosed |
| US-20050171194-A1 | Enlargement of mucocutaneous or cutaneous organs and sites with topical compositions | YU RUEY J (US) | 2005-08-04 | — | — | US | disclosed |
| WO-2005055947-A2 | ENLARGEMENT OF MUCOCUTANEOUS OR CUTANEOUS ORGANS AND SITES WITH TOPICAL COMPOSITIONS | YU RUEY J (US) | 2005-06-23 | — | — | WO | disclosed |
| US-6808716-B2 | N-acetylamino acids, related N-acetyl compounds and their topical use | YU RUEY J (US) | 2004-10-26 | — | — | US | disclosed |
| WO-2004089329-A2 | TOPICAL COMPOSITIONS COMPRISING N-ACETYLAMINO ACIDS OR RELATED N-ACETYL COMPOUNDS | YU RUEY J (US) | 2004-10-21 | — | — | WO | disclosed |
| US-6703031-B1 | OXIDATIVE STRESS INHIBITOR; RETARDING AGING OF SKIN | AJINOMOTO CO., INC. (JP) | 2004-03-09 | — | — | US | disclosed |
| US-20030229141-A1 | N-acetyl cysteine and its topical use | YU RUEY J (US) | 2003-12-11 | — | — | US | disclosed |
| US-20030198656-A1 | N-acetylamino acids, related N-acetyl compounds and their topical use | YU RUEY J (US) | 2003-10-23 | — | — | US | disclosed |
| US-6602492-B2 | Cysteine derivatives | AJINOMOTO CO., INC. (JP) | 2003-08-05 | — | — | US | disclosed |
| EP-1120407-A1 | CYSTEINE DERIVATIVES | Ajinomoto Co., Inc. (JP) | 2001-08-01 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120046232-A1 | COMPOSITIONS AND METHODS FOR REDUCING RELAPSE OF ADDICTIVE BEHAVIOR | GRM6, GRM5, GRM7 | KDM4E 1271/4885MAPT 3237/4885THRB 1739/4885 |
| US-20250332135-A1 | Aggrelytes for Treating Ocular Conditions | AADAC, MGMT, MGST3 | KDM4E 3225/4885MAPT 375/4885THRB 3149/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.