Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGAM | O43451 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13358959 | 0.87 | MGAM (0.45) | MGAMLMNATHRBTDP1 | |
| SCHEMBL4361137 | 0.87 | MGAM (0.45) | MGAMLMNATHRBTDP1 | |
| SCHEMBL12657731 | 0.87 | MGAM (0.45) | MGAMLMNATHRBTDP1 | |
| SCHEMBL12180777 | 0.87 | MGAM (0.45) | MGAMLMNATHRBTDP1 | |
| SCHEMBL21752766 | 0.84 | LMNA (0.43) | MGAMLMNATHRBTSHR | |
| SCHEMBL28204891 | 0.81 | MGAM (0.41) | MGAMLMNATHRB | |
| SCHEMBL10874803 | 0.81 | MGAM (0.41) | MGAMLMNATHRBTSHR | |
| SCHEMBL2829022 | 0.80 | LMNA (0.39) | MGAMLMNATHRBTSHRTDP1 | |
| SCHEMBL14535050 | 0.79 | MGAM (0.41) | MGAMLMNATHRB | |
| SCHEMBL1184726 | 0.79 | MGAM (0.41) | MGAMLMNATHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006057904-A1 | STEREOSELECTIVE PREPARATION OF 4-ARYL PIPERIDINE AMIDES BY ASYMMETRIC HYDROGENATION OF A PROCHIRAL ENAMIDE AND INTERMEDIATES OF THIS PROCESS | MERCK & CO., INC. (US) | 2006-06-01 | — | — | WO | disclosed |